Results 41 to 50 of about 55,212 (214)

MiR-613 suppresses retinoblastoma cell proliferation, invasion, and tumor formation by targeting E2F5

Tumor Biology, 2017
Retinoblastoma is a common intraocular malignancy that occurs during childhood. MicroRNAs play critical roles in the regulation of retinoblastoma initiation and progression, and aberrant expression of miR-613 had been reported in various types of cancer.
Yiting Zhang, Xinyue Zhu, Xiaomin Zhu, Yan Wu, Yajun Liu, Borui Yao, Zhenping Huang   +6 more
doaj   +1 more source

Descolamento da retina após tratamento do retinoblastoma Rhegmatogenous retinal detachment after succesful treatment of retinoblastoma

Revista Brasileira de Oftalmologia, 2010
OBJETIVO: Avaliar a apresentação de descolamento de retina nos pacientes tratados de retinoblastoma no Centro Infantil Dr. Domingos Boldrini - Campinas (SP), Brasil.
João Alberto Holanda de Freitas, Hélio Fernando Heitmann de Abreu, Maristela Amaral Palazzi   +2 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Worldwide Burden of Retinoblastoma from 1990 to 2021

Ophthalmic Research
Introduction: The aim of the study was to report the global, regional, and national burden of retinoblastoma between 1990 and 2021, by age, sex, and sociodemographic index (SDI). Methods: We leveraged the Global Burden of Disease 2021 Study to
Yaling Feng, Xiaoyi Feng, Yun Lv
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Patient knowledge, experiences and preferences regarding retinoblastoma and research: A qualitative study

Health Expectations, 2020
Background We launched a patient engagement strategy to facilitate research involvement of the retinoblastoma (childhood eye cancer) community in Canada.
Catherine Moses, Kaitlyn Flegg, Helen Dimaras   +2 more
doaj   +1 more source

Knockdown of NRMT enhances sensitivity of retinoblastoma cells to cisplatin through upregulation of the CENPA/Myc/Bcl2 axis

Cell Death Discovery, 2022
Chemotherapy resistance of tumor cells causes failure in anti-tumor therapies. Recently, N-terminal regulator of chromatin condensation 1 methyltransferase (NRMT) is abnormally expressed in different cancers.
Zhongrui Li, Lan Zhang, Dongrui Liu, Zhanghui Yang, Di Xuan, Yi Zhang   +5 more
doaj   +1 more source

Retinoblastoma in an adult

Journal of Cytology, 2018
Retinoblastoma is a rare malignant tumor of the retina usually seen in children before 5 years of age. The tumor is extremely rare in adults. We report here an unusual case of retinoblastoma in a 55-year-old adult female who presented to us with an orbital mass at a late stage of the disease. Detailed laboratory investigations and imaging studies could
Vasudha Garg, Ashumi Gupta, Sonam K Pruthi, Pratima Khare   +3 more
openaire   +3 more sources

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Case Series on Imaging Features of Trilateral and Quadrilateral Retinoblastoma: What Radiologists Need to Know

International Journal of Integrated Health Sciences
Objective: To identify the differences between trilateral and quadrilateral retinoblastoma based on radiologic imaging. Case: We found three cases of retinoblastoma at Sanglah General Hospital.
Fiona Fiona, Pande Putu Yuli Anandasari, Ni Nyoman Margiani   +2 more
doaj   +1 more source