Results 31 to 40 of about 66,792 (243)

Magnetic Resonance Imaging Can Reliably Differentiate Optic Nerve Inflammation from Tumor Invasion in Retinoblastoma with Orbital Cellulitis [PDF]

, 2022
PURPOSE To investigate the prevalence and magnetic resonance imaging (MRI) phenotype of retinoblastoma-associated orbital cellulitis. Additionally, this study aimed to identify postlaminar optic nerve enhancement (PLONE) patterns differentiating ...
Sirin, Selma, Biewald, E., de Jong, Marcus C, Maeder, Philippe, Sen, Saugata, Sen, S., de Graaf, P., Castelijns, Jonas A, de Graaf, Pim, Cardoen, Liesbeth, Castelijns, J.A., van der Heide, Sophie, Cardoen, L., Galluzzi, P., Moll, A.C., Jansen, R.W., Brisse, H.J., Galluzzi, Paolo, European Retinoblastoma Imaging Collaboration, Jansen, Robin W, Brisse, Hervé J, Biewald, Eva, Maeder, P., Moll, Annette C, Sirin, S., de Bloeme, C.M., Göricke, Sophia, van der Heide, S., van der Valk, P., van der Valk, Paul, de Jong, M.C., Göricke, S., de Bloeme, Christiaan M   +32 more
core   +1 more source

Retinoblastoma in Late Childhood

Journal of Nepal Medical Association, 2003
Retinoblastoma, the commonest intra-ocular tumor of childhood, is rare after the age of 5 years. We report a case of retinoblastoma in a 10 year-old boy, who presented with a fungating proptosed tender mass involving the entire left eye and the orbit.
B Badhu, S P Sah, S Kumar, R P Sah
doaj   +1 more source

The retinoblastoma protein modulates Tbx2 functional specificity [PDF]

, 2010
Tbx2 is a member of a large family of transcription factors defined by homology to the T-box DNA-binding domain. Tbx2 plays a key role in embryonic development, and in cancer through its capacity to suppress senescence and promote invasiveness.
Colin R. Goding, Goding, CR, Heather M. Shaw, Sascha Ott, Keith W. Vance, Vance, KW, Shaw, HM, Mercedes Rodriguez, Ott, S, Rodriguez, Mercedes, Goding, Colin R., Ott, Sascha, Shaw, Heather M., Rodriguez, M, Vance, Keith W.   +14 more
core   +1 more source

Analysis of MDM2 and MDM4 single nucleotide polymorphisms, mRNA splicing and protein expression in retinoblastoma. [PDF]

PLoS ONE, 2012
Retinoblastoma is a childhood cancer of the developing retina that begins in utero and is diagnosed in the first years of life. Biallelic RB1 gene inactivation is the initiating genetic lesion in retinoblastoma.
Justina McEvoy, Anatoly Ulyanov, Rachel Brennan, Gang Wu, Stanley Pounds, Jinghui Zhang, Michael A Dyer   +6 more
doaj   +1 more source

Expression of MMP-14 and CD44 associated with proliferation of retinoblastoma cells

Medicine Science, 2019
Retinoblastoma is a the most common primary intraocular malignant tumor in childhood. The eexpressions of CD44 and MMP-14 and Their role in proliferation and migration cells appear crucial for retinoblastoma invasion.
Hendrian D. Soebagjo, Evelyn Komaratih, Susy Fatmariyanti, Nurwasis Nurwasis, Aulanniam Aulanniam   +4 more
doaj   +1 more source

Retinoblastoma and vision [PDF]

Eye, 2022
AbstractThe assessment of vision has a growing importance in the management of retinoblastoma in the era of globe-conserving therapy, both prior to and after treatment. As survival rates approach 98–99% and globe salvage rates reach ever-higher levels, it is important to provide families with information regarding the visual outcomes of different ...
Omar Warda, Zishan Naeem, Kelsey A. Roelofs, Mandeep S. Sagoo, M. Ashwin Reddy   +4 more
openaire   +3 more sources

Retinoblastoma genetics in India: From research to implementation

Indian Journal of Ophthalmology, 2015
Retinoblastoma is the prototypic genetic cancer. India carries the biggest burden of retinoblastoma globally, with an estimated 1500 new cases annually.
Helen Dimaras
doaj   +1 more source

Update on pathology of retinoblastoma [PDF]

International Journal of Ophthalmology, 2018
Retinoblastoma is caused by mutational inactivation of both alleles of the RB1 gene, which maps to chromosome 13q14 and encodes retinoblastoma protein that acts as a tumor suppressor.
Lata Singh, Seema Kashyap
doaj   +1 more source

Diffuse infiltrating retinoblastoma invading subarachnoid space [PDF]

, 2011
We report herein an unusual case of diffuse infiltrating retinoblastoma involving the brain, which caused a patient’s death 27 months after enucleation. An eight-year-old boy complained of blurred vision in his right eye (OD) in October 2006. Funduscopic
Suzuki, Shigenobu, Yoshida, Kazuhiko, Ohno, Shigeaki, Kase, Satoru, Ishida, Susumu   +4 more
core   +3 more sources

A rare case of adult onset retinoblastoma

Oman Journal of Ophthalmology, 2011
Retinoblastoma usually manifests before five years of age. Retinoblastoma in an adult is extremely rare. Twenty-three cases of retinoblastoma in adults 20 years or older have been reported in world literature.
Sunil Kumar Singh, Dipankar Das, Harsha Bhattacharjee, Jyotirmay Biswas, Ganesh Kuri, Kasturi Bhattacharjee, Hemlata Deka, Akshay Chandra Deka   +7 more
doaj   +1 more source