Results 91 to 100 of about 1,095,316 (316)

Quantum deletion: Beyond the no-deletion principle [PDF]

Physical Review A, 2005
Suppose we are given two identical copies of an unknown quantum state and we wish to delete one copy from among the given two copies. The quantum no-deletion principle restricts us from perfectly deleting a copy but it does not prohibit us from deleting a copy approximately.
openaire   +2 more sources

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Coordinate Deletion of Zeroes [PDF]

The Electronic Journal of Combinatorics, 2019
For a family $A\subseteq\left\{ 0,\dots,k\right\} ^{n}$, define the $\delta$-shadow of $A$ to be the set obtained from $A$ by removing from any of its vectors one coordinate that equals zero. Given the size of $A$, how should we choose $A$ to minimise its $\delta$-shadow?
openaire   +3 more sources

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Optimality Theoretic Account of Acquisition of Consonant Clusters of English Syllables by Persian EFL Learners [PDF]

Journal of English Language Teaching and Learning, 2010
This study accounts for the acquisition of the consonant clusters of English syllable structures both in onset and coda positions by Persian EFL learners.
Ali Akbar Jabbari, Leila Arghavan
doaj  

ALU transposition induces familial hypertrophic cardiomyopathy

Molecular Genetics & Genomic Medicine, 2020
Background Hypertrophic cardiomyopathy (HCM) is characterized by left ventricular hypertrophy (LVH) in the absence of predisposing cardiovascular conditions. Pathogenic variants in at least 16 cardiac sarcomeric genes have been implicated in HCM, most of
Landry Nfonsam, Lijia Huang, Nancy Carson, Jean McGowan‐Jordan, Melanie Beaulieu Bergeron, Sharan Goobie, Susan Conacher, David McCarty, Lee Benson, Stacy Hewson, Laura Zahavich, Elizabeth Sinclair‐Bourque, Amanda Smith, Ryan Potter, Mahdi Ghani, Lucas Bronicki, Olga Jarinova   +16 more
doaj   +1 more source

Effects of copy number variations on brain structure and risk for psychiatric illness: Large‐scale studies from the ENIGMAworking groups on CNVs

, 2022
The Enhancing NeuroImaging Genetics through Meta‐Analysis copy number variant (ENIGMA‐CNV) and 22q11.2 Deletion Syndrome Working Groups (22q‐ENIGMA WGs) were created to gain insight into the involvement of genetic factors in human brain development and ...
Ge, T., Boomsma, D., Grabe, H., Jalbrzikowski, M., McDonald-McGinn, D., Hashimoto, R., Holmes, A., Vassos, E., Stefánsson, K., Martínez, K., Mathias, S., Paus, T., Rodriguez‐Herreros, B., Draganski, B. ; https://orcid.org/, Van der Meer, D., Liu, J., Craig, M., Hottenga, J., Amunts, K., Ayesa‐Arriola, R., Hansen, L., Armstrong, N., Chow, E., Vila‐Rodriguez, F., Westlye, L., van Ent, D., Bassett, A., Espeseth, T., Glahn, D., Vila-Rodriguez, F., Reis Marques, T., Jacquemont, S., Monereo Sánchez, J., Arango, C., Prieto, C., Ching, C., Roalf, D., Draganski, B., Calhoun, V., Rucker, J., Moreau, C., Wittfeld, K., Mather, K., Gutman, B., Cichon, S., Ulfarsson, M., Tamnes, C., Thompson, P., Reymond, A., Crespo‐Facorro, B., Djurovic, S., Repetto, G., Walters, G., Vajdi, A., Sun, D., Haavik, J., Pol, H., Gur, R., Rodriguez-Herreros, B., Vázquez-Bourgon, J., Sánchez, J., Crespo-Facorro, B., Stefansson, H., Agartz, I., McDonald‐McGinn, D., Bearden, C., Donohoe, G., Sønderby, I., Hulshoff Pol, H., Ehrlich, S., Kushan, L., Thomopoulos, S., Cunningham, A., Silva, A., McRae, A., Modenato, C., Moberget, T., Butcher, N., Martin‐Brevet, S., Zackai, E., Lundervold, A., Marques, T., Van den Bree, M., Dale, A., Hibar, D., Martin-Brevet, S., Mühleisen, T., Schmitt, J., Villalon‐Reina, J., Vázquez‐Bourgon, J., Medland, S., Ciufolini, S., Knowles, E., Pausova, Z., Bakker, G., Villalon-Reina, J., Linden, D., Wen, W., Bülow, R., Doherty, J., Emanuel, B., Van 't Ent, D., Stein, D., Tordesillas-Gutiérrez, D., Fisher, S., Andreassen, O., Håberg, A., Ragothaman, A., Reinbold, C., Tordesillas‐Gutiérrez, D., Caspers, S., De Zubicaray, G., Ayesa-Arriola, R., Schofield, P., Sachdev, P., Durdle, C., Dazzan, P.   +116 more
core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Real-time PCR based on SYBR-Green I fluorescence: An alternative to the TaqMan assay for a relative quantification of gene rearrangements, gene amplifications and micro gene deletions

BMC Biotechnology, 2003
Background Real-time PCR is increasingly being adopted for RNA quantification and genetic analysis. At present the most popular real-time PCR assay is based on the hybridisation of a dual-labelled probe to the PCR product, and the development of a signal
Puisieux Alain, Combaret Valerie, Bell Sandra M, Field Sarah L, Douglas Susan H, Leong Fong T, Bransfield Kieran, Toomes Carmel, Ponchel Frederique, Mighell Alan J, Robinson Philip A, Inglehearn Chris F, Isaacs John D, Markham Alex F   +13 more
doaj   +1 more source

C-C Chemokine Receptor 5 and HIV: Therapeutic Potentials of the Δ32 Base Pair Deletion

, 2011
The human immunodeficiency virus, a retrovirus discovered in 1981, has reached pandemic status worldwide. Without an existing cure or vaccine, a majority of the world’s population remains at risk for infection and more than 35 million people to date have
Antczak, Amanda R.
core