Results 1 to 10 of about 783,434 (219)

SIns: A Novel Insertion Detection Approach Based on Soft-Clipped Reads

Frontiers in Genetics, 2021
As a common type of structural variation, an insertion refers to the addition of a DNA sequence into an individual genome and is usually associated with some inherited diseases.
Chaokun Yan, Junyi He, Junwei Luo, Jianlin Wang, Ge Zhang, Huimin Luo   +5 more
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Profiling variable-number tandem repeat variation across populations using repeat-pangenome graphs

Nature Communications, 2021
Variable number tandem repeats (VNTRs) are difficult to analyze by short-read sequencing in disease studies. Here, the authors describe a VNTR mapping strategy for short-read analyses using a repeat pangenome graph.
Tsung-Yu Lu, The Human Genome Structural Variation Consortium, Mark J. P. Chaisson   +2 more
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The effects of common structural variants on 3D chromatin structure

BMC Genomics, 2020
Background Three-dimensional spatial organization of chromosomes is defined by highly self-interacting regions 0.1–1 Mb in size termed Topological Associating Domains (TADs).
Omar Shanta, Amina Noor, Human Genome Structural Variation Consortium (HGSVC), Jonathan Sebat   +3 more
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SINE Insertion in the Intron of Pig GHR May Decrease Its Expression by Acting as a Repressor

Animals, 2021
The genetic diversity of the GH/IGF axis genes and their association with the variation of gene expression and phenotypic traits, principally represented by SNPs, have been extensively reported.
Cai Chen, Yao Zheng, Mengli Wang, Eduard Murani, Enrico D’Alessandro, Ali Shoaib Moawad, Xiaoyan Wang, Klaus Wimmers, Chengyi Song   +8 more
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Identification of gene family members and a key structural variation reveal important roles of OVATE genes in regulating tea (Camellia sinensis) leaf development

Frontiers in Plant Science, 2022
OVATE genes are a new class of transcriptional repressors with important regulatory roles in plant growth and development. Through genome-wide analysis of the OVATE gene family of tea plants, 26 and 13 family members were identified in cultivated and ...
Yanlin An, Xiaobo Xia, Tingting Jing, Feng Zhang   +3 more
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Patient-Specific Assays Based on Whole-Genome Sequencing Data to Measure Residual Disease in Children With Acute Lymphoblastic Leukemia: A Proof of Concept Study

Frontiers in Oncology, 2022
Risk-adapted treatment in acute lymphoblastic leukemia (ALL) relies on genetic information and measurable residual disease (MRD) monitoring. In this proof of concept study, DNA from diagnostic bone marrow (BM) of six children with ALL, without ...
Cecilia Arthur, Cecilia Arthur, Fatemah Rezayee, Fatemah Rezayee, Nina Mogensen, Nina Mogensen, Leonie Saft, Leonie Saft, Richard Rosenquist, Richard Rosenquist, Magnus Nordenskjöld, Magnus Nordenskjöld, Arja Harila-Saari, Emma Tham, Emma Tham, Gisela Barbany, Gisela Barbany   +16 more
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Ten new high-quality genome assemblies for diverse bioenergy sorghum genotypes

Frontiers in Plant Science, 2023
IntroductionSorghum (Sorghum bicolor (L.) Moench) is an agriculturally and economically important staple crop that has immense potential as a bioenergy feedstock due to its relatively high productivity on marginal lands.
William G. Voelker, William G. Voelker, Krittika Krishnan, Krittika Krishnan, Kapeel Chougule, Louie C. Alexander, Louie C. Alexander, Zhenyuan Lu, Andrew Olson, Doreen Ware, Doreen Ware, Kittikun Songsomboon, Kittikun Songsomboon, Cristian Ponce, Cristian Ponce, Zachary W. Brenton, Zachary W. Brenton, J. Lucas Boatwright, J. Lucas Boatwright, Elizabeth A. Cooper, Elizabeth A. Cooper   +20 more
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Complete Genome Sequence Reveals Evolutionary and Comparative Genomic Features of Xanthomonas albilineans Causing Sugarcane Leaf Scald

Microorganisms, 2020
Leaf scald (caused by Xanthomonas albilineans) is an important bacterial disease affecting sugarcane in most sugarcane growing countries, including China. High genetic diversity exists among strains of X. albilineans from diverse geographic regions.
Hui-Li Zhang, Mbuya Sylvain Ntambo, Philippe C. Rott, Gongyou Chen, Li-Lan Chen, Mei-Ting Huang, San-Ji Gao   +6 more
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Global whole-genome comparison and analysis to classify subpopulations and identify resistance genes in weedy rice relevant for improving crops

Frontiers in Plant Science, 2023
Common weedy rice plants are important genetic resources for modern breeding programs because they are the closest relatives to rice cultivars and their genomes contain elite genes.
Zhenyun Han, Fei Li, Weihua Qiao, Weihua Qiao, Xiaoming Zheng, Xiaoming Zheng, Xiaoming Zheng, Yunlian Cheng, Lifang Zhang, Jingfen Huang, Yanyan Wang, Danjing Lou, Meng Xing, Weiya Fan, Yamin Nie, Wenlong Guo, Shizhuang Wang, Ziran Liu, Qingwen Yang, Qingwen Yang   +19 more
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Oat chromosome and genome evolution defined by widespread terminal intergenomic translocations in polyploids

Frontiers in Plant Science, 2022
Structural chromosome rearrangements involving translocations, fusions and fissions lead to evolutionary variation between species and potentially reproductive isolation and variation in gene expression.
Paulina Tomaszewska, Paulina Tomaszewska, Trude Schwarzacher, Trude Schwarzacher, J. S. (Pat) Heslop-Harrison, J. S. (Pat) Heslop-Harrison   +5 more
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