Results 31 to 40 of about 725,686 (267)

Structural and transduction patterns of human-specific polymorphic SVA insertions

Mobile DNA
Background SINE variable number tandem repeat Alu elements (SVAs) are a unique group of hominid-specific composite retrotransposons with highly variable internal structure.
Ashley E. Kirby, Mark Loftus, Emily C. Golba, Human Genome Structural Variation Consortium, Miriam K. Konkel   +4 more
doaj   +1 more source

Insights into the Stearoyl-Acyl Carrier Protein Desaturase (SAD) Family in Tigernut (Cyperus esculentus L.), an Oil-Bearing Tuber Plant

Plants
Plant oils rich in oleic acid (OA) are attracting considerable attention for their high nutritional value and significant industrial potential. Stearoyl-acyl carrier protein desaturases (SADs) are a class of soluble desaturases that play a key role in OA
Zhi Zou, Xiaowen Fu, Chunqiang Li, Xiaoping Yi, Jiaquan Huang, Yongguo Zhao   +5 more
doaj   +1 more source

Revisiting Structured Variational Autoencoders

CoRR, 2023
Structured variational autoencoders (SVAEs) combine probabilistic graphical model priors on latent variables, deep neural networks to link latent variables to observed data, and structure-exploiting algorithms for approximate posterior inference.
Yixiu Zhao, Scott W. Linderman
openaire   +3 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Impact and characterization of serial structural variations across humans and great apes

Nature Communications
Modern sequencing technology enables the systematic detection of complex structural variation (SV) across genomes. However, extensive DNA rearrangements arising through a series of mutations, a phenomenon we refer to as serial SV (sSV), remain ...
Wolfram Höps, Tobias Rausch, Michael Jendrusch, Human Genome Structural Variation Consortium (HGSVC), Jan O. Korbel, Fritz J. Sedlazeck   +5 more
doaj   +1 more source

Second harmonic generation polarization microscopy as a tool for protein structure analysis

Biophysics and Physicobiology, 2019
Cryo-electron microscopy and X-ray crystallography have been the major tools of protein structure analysis for decades and will certainly continue to be essential in the future.
Junichi Kaneshiro, Yasushi Okada, Tomohiro Shima, Mika Tsujii, Katsumi Imada, Taro Ichimura, Tomonobu M. Watanabe   +6 more
doaj   +1 more source

Modulational Instability and Variational Structure [PDF]

Studies in Applied Mathematics, 2014
We study the modulational instability of periodic traveling waves for a class of Hamiltonian systems in one spatial dimension. We examine how the Jordan block structure of the associated linearized operator bifurcates for small values of the Floquet exponent to derive a criterion governing instability to long wavelengths perturbations in terms of the ...
Bronski, J. C., Hur, V. M.
openaire   +2 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Evolutionary conservation and enhanced basal immunity of the ZmNBS gene family in maize

Frontiers in Plant Science
The nucleotide-binding site (NBS) gene family is central to plant innate immunity. However, a comprehensive understanding of its evolutionary dynamics and functional diversity in maize, particularly within a pan-genomic context, remains limited.
Zhe Xu, Liying Feng
doaj   +1 more source

Structural variations in plant genomes [PDF]

Briefings in Functional Genomics, 2014
Differences between plant genomes range from single nucleotide polymorphisms to large-scale duplications, deletions and rearrangements. The large polymorphisms are termed structural variants (SVs). SVs have received significant attention in human genetics and were found to be responsible for various chronic diseases.
Saxena, Rachit K., Edwards, David, Varshney, Rajeev K.   +2 more
openaire   +5 more sources