Results 51 to 60 of about 15,084,422 (295)

Current status of structural variation studies in plants

Plant Biotechnology Journal, 2021
Summary Structural variations (SVs) including gene presence/absence variations and copy number variations are a common feature of genomes in plants and, together with single nucleotide polymorphisms and epigenetic differences, are responsible for the ...
Yuxuan Yuan, P. Bayer, J. Batley, D. Edwards   +3 more
semanticscholar   +1 more source

Whole-Genome Resequencing and Pan-Transcriptome Reconstruction Highlight the Impact of Genomic Structural Variation on Secondary Metabolite Gene Clusters in the Grapevine Esca Pathogen Phaeoacremonium minimum

Frontiers in Microbiology, 2018
The Ascomycete fungus Phaeoacremonium minimum is one of the primary causal agents of Esca, a widespread and damaging grapevine trunk disease. Variation in virulence among Pm.
Mélanie Massonnet, Abraham Morales-Cruz, Andrea Minio, Rosa Figueroa-Balderas, Daniel P. Lawrence, Renaud Travadon, Philippe E. Rolshausen, Kendra Baumgartner, Dario Cantu   +8 more
doaj   +1 more source

From genome structure to function: insights into structural variation in microbiology

Current Opinion in Microbiology, 2022
Structural variation in bacterial genomes is an important evolutionary driver. Genomic rearrangements, such as inversions, duplications, and insertions, can regulate gene expression and promote niche adaptation.
P. West, Rachael B. Chanin, A. Bhatt
semanticscholar   +1 more source

A 598-bp InDel Variation in the Promoter Region of Bna.SOC1.A05 Is Predominantly Present in Winter Type Rapeseeds

Frontiers in Plant Science, 2021
During rapeseed domestication and breeding, genetic diversity allowed to adapt it to different eco-geographical regions and to shape its useful traits. Structural variations (SVs), including presence/absence variations (PAVs), are thought to play a major
Sarah Matar, Siegbert Melzer
doaj   +1 more source

Severus detects somatic structural variation and complex rearrangements in cancer genomes using long-read sequencing

Nature Biotechnology
For the detection of somatic structural variation (SV) in cancer genomes, long-read sequencing is advantageous over short-read sequencing with respect to mappability and variant phasing.
A. Keskus, A. Bryant, Tanveer Ahmad, B. Yoo, S. Aganezov, A. Goretsky, A. Donmez, L. Lansdon, Isabel Rodríguez, Jimin Park, Yue-Lin Liu, Xiwen Cui, J. Gardner, B. McNulty, S. Sacco, Jyoti Shetty, Yong-Mei Zhao, B. Tran, Giuseppe Narzisi, Adrienne Helland, Daniel E. Cook, Pi-Chuan Chang, Alexey Kolesnikov, Andrew Carroll, E. Molloy, Cheng-Peng Bi, Adam M. Walter, M. Gibson, I. Pushel, Erin M. Guest, T. Pastinen, Kishwar Shafin, K. Miga, S. Malikić, Chi-Ping Day, N. Robine, C. Sahinalp, Michael C. Dean, M. Farooqi, Benedict Paten, M. Kolmogorov   +40 more
semanticscholar   +1 more source

Identification of structural variation in mouse genomes. [PDF]

, 2014
Structural variation is variation in structure of DNA regions affecting DNA sequence length and/or orientation. It generally includes deletions, insertions, copy-number gains, inversions, and transposable elements.
Reymond, Alexandre, Thomas M Keane, Jonathan Flint, Jonathan eFlint, Reymond, A., Kim Wong, Keane, T.M., Alexandre eReymond, Adams, D.J., Adams, David, Yalcin, Binnaz, Keane, Thomas, Alexandre Reymond, Binnaz Yalcin, David J. Adams, Wong, K., Kim eWong, Flint, Jonathan, Yalcin, B., Flint, J., David J Adams, Binnaz eYalcin, Thomas M. Keane, Wong, Kim, Flint J, Yalcin B, Adams DJ, Wong K, Reymond A, Keane TM   +29 more
core   +1 more source

Structural variation in 1,019 diverse humans based on long-read sequencing

Nature
Genomic structural variants (SVs) contribute substantially to genetic diversity and human diseases1, 2, 3–4, yet remain under-characterized in population-scale cohorts5. Here we conducted long-read sequencing6 in 1,019 humans to construct an intermediate-
Siegfried Schloissnig, Samarendra Pani, Jana Ebler, C. Hain, Vasiliki Tsapalou, Arda Söylev, P. Hüther, Hufsah Ashraf, Timofey Prodanov, Mila Asparuhova, H. Magalhães, Wolfram Höps, J. Sotelo-Fonseca, T. Fitzgerald, Walter Santana-Garcia, R. Moreira-Pinhal, Sarah E. Hunt, F. Pérez-Llanos, T. Wollenweber, S. Sivalingam, Dagmar Wieczorek, Mario Cáceres, C. Gilissen, E. Birney, Z. Ding, J. Jensen, N. Podduturi, J. Stutzki, B. Rodriguez-Martin, T. Rausch, T. Marschall, J. Korbel   +31 more
semanticscholar   +1 more source

Recent advances and current challenges in population genomics of structural variation in animals and plants

Frontiers in Genetics, 2022
The field of population genomics has seen a surge of studies on genomic structural variation over the past two decades. These studies witnessed that structural variation is taxonomically ubiquitous and represent a dominant form of genetic variation ...
Ivana Pokrovac, Ž. Pezer
semanticscholar   +1 more source

Copy number variation, chromosome rearrangement, and their association with recombination during avian evolution [PDF]

, 2010
Chromosomal rearrangements and copy number variants (CNVs) play key roles in genome evolution and genetic disease; however, the molecular mechanisms underlying these types of structural genomic variation are not fully understood.
Skinner, Benjamin M., Bunzey, Sydney K., Ellegren, Hans, Völker, Martin, Backström, Niclas, Langley, Elizabeth J, Griffin, Darren K., Skinner, Benjamin M, Bunzey, Sydney K, Griffin, Darren K, Ellegren, Hans,, Backström, Niclas,   +11 more
core   +1 more source

Impacts of allopolyploidization and structural variation on intraspecific diversification in Brassica rapa

Genome Biology, 2021
Background Despite the prevalence and recurrence of polyploidization in the speciation of flowering plants, its impacts on crop intraspecific genome diversification are largely unknown.
Xu Cai, Li-Chun Chang, Tingting Zhang, Haixu Chen, Lei Zhang, Runmao Lin, Jianli Liang, Jian Wu, M. Freeling, Xiao-Wu Wang   +9 more
semanticscholar   +1 more source