Results 61 to 70 of about 5,946,777 (312)

Sorting out Sortilins: structural studies on the VPS10 family [PDF]

open access: yes, 2017
The topic of this dissertation is the structural characterization of the VPS10 receptors Sortilin and SorCS2, as well as their interactions with proneurotrophins.
Sub Crystal and Structural Chemistry   +2 more
core  

Visualizing Population Structure with Variational Autoencoders [PDF]

open access: yesG3 Genes|Genomes|Genetics, 2020
Abstract Dimensionality reduction is a common tool for visualization and inference of population structure from genotypes, but popular methods either return too many dimensions for easy plotting (PCA) or fail to preserve global geometry (t-SNE and UMAP). Here we explore the utility of variational autoencoders (VAEs) –
C J Battey   +2 more
openaire   +4 more sources

The complete chloroplast genome sequence of Enkianthus perulatus (Miq.) C.K.Schneid. (Ericaceae)

open access: yesMitochondrial DNA. Part B. Resources
Enkianthus perulatus (Miq.) C.K.Schneid. is a popular ornamental plant in Japan, for which the chloroplast genome has not been previously reported. Its complete chloroplast genome was therefore determined, using a high-throughput sequencing technique ...
Watanabe Yoichi
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Modulational Instability and Variational Structure [PDF]

open access: yesStudies in Applied Mathematics, 2014
We study the modulational instability of periodic traveling waves for a class of Hamiltonian systems in one spatial dimension. We examine how the Jordan block structure of the associated linearized operator bifurcates for small values of the Floquet exponent to derive a criterion governing instability to long wavelengths perturbations in terms of the ...
Bronski, J. C., Hur, V. M.
openaire   +2 more sources

Multiple copy number variants of VC1 gene reveal single-copy expression as a key determinant of vicine content

open access: yesFrontiers in Plant Science
Faba bean is a valuable legume crop desired globally for its high nutritional composition. However, the seed vicine and convicine (v-c) content reduces the nutritional quality of faba bean protein and can induce favism in susceptible individuals ...
Samson Ugwuanyi   +4 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Variation in the syntax of the partitive structure

open access: yesAnnual Meeting of the Berkeley Linguistics Society, 2011
Proceedings of the 37th Annual Meeting of the Berkeley Linguistics Society (2013), pp.
Stickney, Helen   +2 more
openaire   +3 more sources

Structural variations in plant genomes [PDF]

open access: yesBriefings in Functional Genomics, 2014
Differences between plant genomes range from single nucleotide polymorphisms to large-scale duplications, deletions and rearrangements. The large polymorphisms are termed structural variants (SVs). SVs have received significant attention in human genetics and were found to be responsible for various chronic diseases.
Saxena, Rachit K.   +2 more
openaire   +5 more sources

Home - About - Disclaimer - Privacy