Results 21 to 30 of about 15,084,422 (295)

Structural Variation in Cancer: Role, Prevalence, and Mechanisms.

Annual review of genomics and human genetics (Print), 2022
Somatic rearrangements resulting in genomic structural variation drive malignant phenotypes by altering the expression or function of cancer genes.
M. R. Cosenza, B. Rodriguez-Martin, J. Korbel   +2 more
semanticscholar   +1 more source

Ten new high-quality genome assemblies for diverse bioenergy sorghum genotypes

Frontiers in Plant Science, 2023
IntroductionSorghum (Sorghum bicolor (L.) Moench) is an agriculturally and economically important staple crop that has immense potential as a bioenergy feedstock due to its relatively high productivity on marginal lands.
William G. Voelker, William G. Voelker, Krittika Krishnan, Krittika Krishnan, Kapeel Chougule, Louie C. Alexander, Louie C. Alexander, Zhenyuan Lu, Andrew Olson, Doreen Ware, Doreen Ware, Kittikun Songsomboon, Kittikun Songsomboon, Cristian Ponce, Cristian Ponce, Zachary W. Brenton, Zachary W. Brenton, J. Lucas Boatwright, J. Lucas Boatwright, Elizabeth A. Cooper, Elizabeth A. Cooper   +20 more
doaj   +1 more source

Cryo-ET of Env on intact HIV virions reveals structural variation and positioning on the Gag lattice

Cell, 2022
Summary HIV-1 Env mediates viral entry into host cells and is the sole target for neutralizing antibodies. However, Env structure and organization in its native virion context has eluded detailed characterization.
Vidya Mangala Prasad, D. Leaman, Klaus N. Lovendahl, Jacob T. Croft, M. Benhaim, Edgar A Hodge, M. Zwick, Kelly K. Lee   +7 more
semanticscholar   +1 more source

Structural variation in the chicken genome identified by paired-end next-generation DNA sequencing of reduced representation libraries [PDF]

, 2011
Background Variation within individual genomes ranges from single nucleotide polymorphisms (SNPs) to kilobase, and even megabase, sized structural variants (SVs), such as deletions, insertions, inversions, and more complex rearrangements.
Kerstens Hindrik HD, Vereijken, A., Martien AM Groenen, Bert W Dibbits, Groenen, M.A.M., Dibbits, B.W., Kerstens, H.H.D., Dibbits Bert W, Okimoto Ron, Hindrik HD Kerstens, Richard PMA Crooijmans, Addie Vereijken, Vereijken Addie, Crooijmans, R.P.M.A., Okimoto, R., Groenen Martien AM, Crooijmans Richard PMA, Ron Okimoto   +17 more
core   +2 more sources

Complete Genome Sequence Reveals Evolutionary and Comparative Genomic Features of Xanthomonas albilineans Causing Sugarcane Leaf Scald

Microorganisms, 2020
Leaf scald (caused by Xanthomonas albilineans) is an important bacterial disease affecting sugarcane in most sugarcane growing countries, including China. High genetic diversity exists among strains of X. albilineans from diverse geographic regions.
Hui-Li Zhang, Mbuya Sylvain Ntambo, Philippe C. Rott, Gongyou Chen, Li-Lan Chen, Mei-Ting Huang, San-Ji Gao   +6 more
doaj   +1 more source

Global whole-genome comparison and analysis to classify subpopulations and identify resistance genes in weedy rice relevant for improving crops

Frontiers in Plant Science, 2023
Common weedy rice plants are important genetic resources for modern breeding programs because they are the closest relatives to rice cultivars and their genomes contain elite genes.
Zhenyun Han, Fei Li, Weihua Qiao, Weihua Qiao, Xiaoming Zheng, Xiaoming Zheng, Xiaoming Zheng, Yunlian Cheng, Lifang Zhang, Jingfen Huang, Yanyan Wang, Danjing Lou, Meng Xing, Weiya Fan, Yamin Nie, Wenlong Guo, Shizhuang Wang, Ziran Liu, Qingwen Yang, Qingwen Yang   +19 more
doaj   +1 more source

Oat chromosome and genome evolution defined by widespread terminal intergenomic translocations in polyploids

Frontiers in Plant Science, 2022
Structural chromosome rearrangements involving translocations, fusions and fissions lead to evolutionary variation between species and potentially reproductive isolation and variation in gene expression.
Paulina Tomaszewska, Paulina Tomaszewska, Trude Schwarzacher, Trude Schwarzacher, J. S. (Pat) Heslop-Harrison, J. S. (Pat) Heslop-Harrison   +5 more
doaj   +1 more source

Genomic Hallmarks and Structural Variation in Metastatic Prostate Cancer

Cell, 2018
Tomasz M Beer, Luke A Gilbert, Marc D. Perry   +2 more
exaly   +2 more sources

Expectations and blind spots for structural variation detection from long-read assemblies and short-read genome sequencing technologies.

American Journal of Human Genetics, 2021
Virtually all genome sequencing efforts in national biobanks, complex and Mendelian disease programs, and medical genetic initiatives are reliant upon short-read whole-genome sequencing (srWGS), which presents challenges for the detection of structural ...
Xue-Fang Zhao, Ryan L. Collins, Wan-Ping Lee, Alexandra M. Weber, Y. Jun, Qi-Hui Zhu, B. Weisburd, Yongqing Huang, P. Audano, Harold Wang, Mark Walker, Chelsea Lowther, Jack M. Fu, M. Gerstein, S. Devine, T. Marschall, J. Korbel, E. Eichler, M. Chaisson, Charles Lee, R. Mills, H. Brand, M. Talkowski   +22 more
semanticscholar   +1 more source

A re-sequencing based assessment of genomic heterogeneity and fast neutron-induced deletions in a common bean cultivar

Frontiers in Plant Science, 2013
A small fast neutron mutant population has been established from Phaseolus vulgaris cv. Red Hawk. We leveraged the available P. vulgaris genome sequence and high throughput next generation DNA sequencing to examine the genomic structure of five ...
Jamie A. O'Rourke, Jamie A. O'Rourke, Luis P. Iniguez, Bruna eBucciarelli, Bruna eBucciarelli, Jeffrey eRoessler, Jeremy eSchmutz, Phillip E. McClean, Scott A. Jackson, Georgina eHernandez, Michelle A. Graham, Robert M. Stupar, Carroll P. Vance, Carroll P. Vance   +13 more
doaj   +1 more source