Results 21 to 30 of about 5,946,777 (312)

Exploring the Relationship Among Divergence Time and Coding and Non-coding Elements in the Shaping of Fungal Mitochondrial Genomes

open access: yesFrontiers in Microbiology, 2020
The order Hypocreales (Ascomycota) is composed of ubiquitous and ecologically diverse fungi such as saprobes, biotrophs, and pathogens. Despite their phylogenetic relationship, these species exhibit high variability in biomolecules production, lifestyle,
Paula L. C. Fonseca   +11 more
doaj   +1 more source

Dissection of Quantitative Blackleg Resistance Reveals Novel Variants of Resistance Gene Rlm9 in Elite Brassica napus

open access: yesFrontiers in Plant Science, 2021
Blackleg is one of the major fungal diseases in oilseed rape/canola worldwide. Most commercial cultivars carry R gene-mediated qualitative resistances that confer a high level of race-specific protection against Leptosphaeria maculans, the causal fungus ...
Paul Vollrath   +10 more
doaj   +1 more source

Design and structural characterisation of olfactomedin-1 variants as tools for functional studies [PDF]

open access: yes, 2019
Background Olfactomedin-1 (Olfm1; also known as Noelin or Pancortin) is a highly-expressed secreted brain and retina protein and its four isoforms have different roles in nervous system development and function.
Sub Crystal and Structural Chemistry   +7 more
core   +2 more sources

A DNA Replication Mechanism Can Explain Structural Variation at the Pigeon Recessive Red Locus

open access: yesBiomolecules, 2022
For species to adapt to their environment, evolution must act upon genetic variation that is present in the population. Elucidating the molecular mechanisms that give rise to this variation is thus of crucial importance for understanding how organisms ...
Jonathan Haddock, Eric T. Domyan
doaj   +1 more source

Patterns of somatic structural variation in human cancer genomes

open access: yes, 2020
A key mutational process in cancer is structural variation, in which rearrangements delete, amplify or reorder genomic segments that range in size from kilobases to whole chromosomes1–7.
PCAWG Structural Variation Working Group   +1 more
core   +1 more source

Insight into mode-of-action and structural determinants of the compstatin family of clinical complement inhibitors [PDF]

open access: yes, 2022
With the addition of the compstatin-based complement C3 inhibitor pegcetacoplan, another class of complement targeted therapeutics have recently been approved.
Berger, Nadja   +11 more
core   +2 more sources

Copy Number Variation Mapping and Genomic Variation of Autochthonous and Commercial Turkey Populations

open access: yesFrontiers in Genetics, 2019
This study aims at investigating genomic diversity of several turkey populations using Copy Number Variants (CNVs). A total of 115 individuals from six Italian breeds (Colle Euganei, Bronzato Comune Italiano, Parma e Piacenza, Brianzolo, Nero d’Italia ...
Maria G. Strillacci   +8 more
doaj   +1 more source

Human Pangenomics: Promises and Challenges of a Distributed Genomic Reference

open access: yesLife, 2023
A pangenome is a collection of the common and unique genomes that are present in a given species. It combines the genetic information of all the genomes sampled, resulting in a large and diverse range of genetic material.
Paolo Abondio   +2 more
doaj   +1 more source

Regional variation in the pronunciation of /s/ in the Dutch language area [PDF]

open access: yes, 2019
This paper reports on an explorative sociophonetic study of the phoneme /s/ in the Dutch language area. Our aim is to investigate the regional variation in the realisation of this phoneme, and to test experimentally the observation of Collins & Mees ...
Heeren, W.F.L.   +6 more
core   +2 more sources

Developmental variation in the structure of the retina [PDF]

open access: yesThe Journal of Neuroscience, 1993
Events traditionally called “developmental errors” are known to occur in both vertebrate and invertebrate nervous systems. This study was concerned with the frequency and mode of generation of such events in the mammalian retina. We studied three anomalous structures observed in the rabbit's retina after staining of the cell populations that accumulate
R H, Masland, J F, Rizzo, J H, Sandell
openaire   +2 more sources

Home - About - Disclaimer - Privacy