Results 211 to 220 of about 1,704,122 (259)

Involvement of the African swine fever virus protein pH108R in virion morphogenesis. [PDF]

Emerg Microbes Infect
Ren J, Zhu G, Wen Y, Ru Y, Tian H, Qi X, Qin X, Shi Z, Zhou Y, Li D, Zheng H.   +10 more
europepmc   +1 more source

Advancing Dry Electroencephalography With Scalable, Soft, and Transcranial Magnetic Stimulation‐Compatible Ti3C2Tx MXene Electrodes for Research and Clinical‐Grade Applications

Advanced Science, EarlyView.
Dry soft Ti3C2Tx MXene electroencephalography (EEG) electrodes provide low impedance (2.1 ± 1.8 kΩ at 10 Hz), long‐term stability, and enable safe simultaneous EEG and transcranial magnetic stimulation (TMS). Across scalp sites, hair types, and recording paradigms, including steady state visual evoked potentials (SSVEP), clinical EEG, and mobile EEG ...
Sneha Shankar, Jakob Michiels, Ksenija Tasich, Ashley Koluda, Ryan Rich, Brian Erickson, Eugenia Angelopoulos, Francesca Cimino, Daryl Hurwitz, Raghav Garg, Spencer R. Averbeck, Doris Xu, Mariam Josyula, Nina Petillo, James J. Gugger, Kathryn A. Davis, John Medaglia, Flavia Vitale   +17 more
wiley   +1 more source

Compound heterozygosity of a novel missense variant and exonic deletion in hypomyelinating leukodystrophy 15. [PDF]

Neurogenetics
Mitsutake A, Matsukawa T, Orimo K, Ueda K, Seki T, Shiio Y, Mitsui J, Ishiura H, Mori H, Tsuji S, Toda T.   +10 more
europepmc   +1 more source

Deletion [PDF]

, 2018
openaire   +1 more source

Farnesyltransferase Deficiency in Cardiomyocytes Initiates Senescence and Contributes to Cardiac Fibrosis

Advanced Science, EarlyView.
Lipid overload suppresses SREBF2‐mediated FNTB expression, leading to defective Lamin A maturation and nuclear envelope instability. This nuclear catastrophe triggers a pro‐fibrotic senescence program in cardiomyocytes. Notably, restoring nuclear integrity via AAV9‐based gene therapy effectively attenuates cardiac remodeling, identifying the ...
Yuxiao Chen, Lian Lou, Xuan Zhang, Lin Yan, Qi Zhang, Wen Shi, Jie Ding, Xu Lin, Rong Jiang, Shuo Liu, Thida Sok, Pengli Wang, Yun Mou, Jie Han, Shenjiang Hu, Xiaogang Guo, Jian Yang   +16 more
wiley   +1 more source

Mitochondrial Pyruvate Metabolism Controls Alveolar Stem Cell Fate and Inflammatory Balance. [PDF]

Inflammation
He Z, Li X, Miao X, Xu G, Wang S, Li L, Wu Q, Chen H.   +7 more
europepmc   +1 more source

PDZK1‐ULK1 Axis Triggers Lipophagy to Inhibit Tumor Progression and Sunitinib Resistance in Clear Cell Renal Cell Carcinoma

Advanced Science, EarlyView.
This study reveals that PDZK1 loss impairs ULK1‐mediated lipophagy, driving lipid droplet accumulation and sunitinib resistance in clear cell renal cell carcinoma. PDZK1 inhibits LEF1 nuclear translocation, enhancing ULK1 transcription. Pharmacological ULK1 activation resensitizes resistant tumors to sunitinib.
Xuan Qi, Yu Guo, Yumeng Yang, Haibo Wang, Xiaomei Yang, Ran Song, Qiong Qin, Yan Zhang, Meihan Hu, Haixing Zhou, Duiping Feng, Junqi He   +11 more
wiley   +1 more source

Selective deletion of FGFR1 in AgRP neurons impairs energy homeostasis under high-fat diet in mice. [PDF]

Mol Metab
Shookster D, O'Connell S, Darshan P, Landry T, Bunner W, Jiang Z, Tong Q, Huang H.   +7 more
europepmc   +1 more source

Amyloid β Instigates Cardiac Neurotrophic Signaling Impairment, Driving Alzheimer's Associated Heart Disease

Advanced Science, EarlyView.
This research identified cardiac amyloid pathology, neurotrophic factor depletion, and reduced myocardial nerve function in a transgenic model of cerebral amyloidosis (Tg2576), Aβ‐challenged cardiomyocytes, and in human AD heart tissue. These findings carry significant diagnostic and therapeutic implications, emphasizing the role of neuro‐signaling ...
Andrea Elia, Rebecca Parodi‐Rullan, Rafael Vazquez‐Torres, Ashley Carey, Huaqing Zhao, Sabzali Javadov, Silvia Fossati   +6 more
wiley   +1 more source