UGA4 and YBR062C Regulate Oxidative Stress Tolerance Under Heavy Metal Toxicity. [PDF]
Al-Gafari M +8 more
europepmc +1 more source
Streptococcus anginosus extracellular vesicles (SA‐EVs) accumulate in gastric tissue, disrupt epithelial tight junctions, and induce gastritis characterized by neutrophil infiltration and elevated cytokines (TNF‐α, IL‐6, IL‐17A). Proteomics identifies TMPC and FBP62 as key SA‐EVs virulence factors; their genetic deletion attenuates inflammation ...
Ying Gong +12 more
wiley +1 more source
Assay for numerical and graphical detection of Native American mitochondrial haplogroup B with real-time PCR. [PDF]
Ramírez-Molina RM +2 more
europepmc +1 more source
Tumor evolution in lung adenocarcinoma is shaped by genetic alterations and spatial immune dynamics. By integrating whole‐exome sequencing, imaging mass cytometry, and spatial transcriptomics across two mouse models, this study reveals how mutational burden, immune infiltration, and cell–state interactions evolve during early and late carcinogenesis ...
Bo Zhu +34 more
wiley +1 more source
CRISPR-Cas9-driven genome editing in <i>Bacillus methanolicus</i> MGA3. [PDF]
Khider MLK +8 more
europepmc +1 more source
Selective Targeting of Tip Endothelial Cells as a Therapeutic Strategy for Tumor Angiogenesis
Doppel protein is selectively expressed in tip endothelial cells within the tumor vasculature, where it promotes tip cell motility and stabilizes the tip cell phenotype. Targeting Doppel with monoclonal antibodies disrupts this stabilization, impairs angiogenic sprouting, and reduces tumor angiogenesis, offering a selective and druggable switch for ...
Byoungmo Kim +16 more
wiley +1 more source
Currarino syndrome associated with an isolated 7q terminal deletion in Korea: a case report. [PDF]
Jung JH, Jeong J, Kim SH.
europepmc +1 more source
Vacuole and mitochondria patch (vCLAMP) protein Mcp1 reduces the pathogenesis of Candida albicans by impeding the function of Cap1-mediated oxidative stress response. [PDF]
Wei Y, Mao X.
europepmc +1 more source
Effects of the type V secretion system eYadA on the biological properties and pathogenicity of avian pathogenic Escherichia coli. [PDF]
Xia P +7 more
europepmc +1 more source

