Results 81 to 90 of about 45,922 (283)

From core belief challenge to posttraumatic growth in para sport athletes: moderated mediation by needs satisfaction and deliberate rumination [PDF]

open access: yes, 2018
Purpose: To examine how deliberate rumination and psychological need satisfaction interact to facilitate posttraumatic growth for para sport athletes with acquired disability.
Wadey, Ross   +11 more
core   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Adaptive and Incremental-Clustering Anomaly Detection Algorithm for VMs Under Cloud Platform Runtime Environment

open access: yesIEEE Access, 2018
The advent of cloud platform has promoted the complexity and scales of industries increasingly. Any deliberate or non-deliberate faults may cause enormous impact on system performance and server costs.
Hancui Zhang, Jun Liu, Tianshu Wu
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Students as informal leaders in deliberate acts of inclusion

open access: yes, 2022
This article focuses on the importance of highlighting students’ role as informal leaders and their efforts to take on active roles in decision-making processes.
Christina H., Sorkos G.
core   +1 more source

The role of laboratories in mitigating the threat of Security Sensitive Biological Agents to animal health and agriculture [PDF]

open access: yesMicrobiology Australia, 2020
The aim of Australia’s Security Sensitive Biological Agents (SSBAs) Regulatory Scheme is to limit opportunities for acts of bioterrorism or criminal acts using harmful biological agents.
Debbie Eagles
doaj  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

How do families represent the functions of deliberate self-harm? A comparison between the social representations from Adolescents and Their Parents [PDF]

open access: yes, 2019
Research has recognized the importance of understanding the social representations about the functions of deliberate self-harm, particularly in the context of clinical intervention.
Pereira, M. Gouveia   +3 more
core   +1 more source

On the origins and consequences of natural play and performing arts practices

open access: yesHumanities & Social Sciences Communications
Natural play (NP) is one key to survival in the animal kingdom. Human play serves to protect children’s mental and physical wellbeing. Taxonomies of NP suggest that some forms map onto performing arts practices (PAP) such as, for example, singing ...
Gunter Kreutz
doaj   +1 more source

A Review of Amelia Walker, Helen Grimmett, and Alison L. Black’s, Ludic Inquiries Into Power and Pedagogy in Higher Education: How Games Play Us

open access: yesArt/Research International
This narrative offering, interwoven with poetry, is my response to Walker, Grimmett, and Black’s (2024) edited volume Ludic Inquiries into Power and Pedagogy in Higher Education: How Games Play Us.
Sharon McDonough
doaj   +1 more source

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