Results 51 to 60 of about 7,352,360 (403)

On the mechanism of tissue-specific mRNA delivery by selective organ targeting nanoparticles

Proceedings of the National Academy of Sciences of the United States of America, 2021
Significance Liver accumulation represents a significant barrier in the development of therapeutically efficacious nanoparticle drug delivery systems. Using a series of lipid nanoparticles with distinct organ-targeting properties, we provide evidence for
Sean A. Dilliard, Qiang Cheng, D. Siegwart   +2 more
semanticscholar   +1 more source

Personalizing the Pediatric Hematology/Oncology Fellowship: Adapting Training for the Next Generation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT The pediatric hematology‐oncology fellowship training curriculum has not substantially changed since its inception. The first year of training is clinically focused, and the second and third years are devoted to scholarship. However, this current structure leaves many fellows less competitive in the current job market, resulting in ...
Scott C. Borinstein, Melissa J. Rose, Scott Moerdler, Richard Ho   +3 more
wiley   +1 more source

Transforming Front-Line Child Welfare Practice: The Impacts of Institutional Settings on Services, Employment Environments, Children, and Families (SYNTHESIS REPORT) [PDF]

, 2010
In 2006, the Ontario government launched an ambitious and multi-faceted Transformation Agenda for child welfare services. Among this Agenda’s objectives was the development of more cooperative helping relationships in child welfare, reducing the system’s
Cameron, Gary, Frensch, Karen, Hazineh, Lirondel   +2 more
core   +4 more sources

Coronaeconomics: a New World After the Pandemic

Informaciâ i Innovacii, 2020
The multifactorial systemic crisis resulting from the COVID-19 coronavirus pandemic is causing critical changes in a number of sectors of the world economy. The author analyses the opinions of leading domestic and foreign experts on this topic.
A. S. Genkin
doaj   +1 more source

A Comparative Contemplation on the Rule regarding the Destruction of the Object of the Sale before Delivery in Article 387 of the Iranian Civil Code: A Comparative Study of Imamiah Jurisprudence, Iranian Law and CISG [PDF]

پژوهش تطبیقی حقوق اسلام و غرب, 2017
Article 387 of the Iranian Civil Code, following the Imamiah thinkers, has prescribed the termination of sale in the case of the destruction of sold object before delivery to buyer without seller's encroachment or negligence. Now, the question is whether
Sayyed Abdol Motalleb Ahmad Zade Bazzaz, Sayyed Mohammad Hadi Ghabooli Dorafshan, sayyed mohammad sadegh Ghabooli Dorafshan   +2 more
doaj   +1 more source

Advances in Oral Drug Delivery

Frontiers in Pharmacology, 2021
The oral route is the most common route for drug administration. It is the most preferred route, due to its advantages, such as non-invasiveness, patient compliance and convenience of drug administration.
Mohammed S. Alqahtani, Mohsin Kazi, Mohammad Alsenaidy, Muhammad Z. Ahmad   +3 more
semanticscholar   +1 more source

The MedSupport Multilevel Intervention to Enhance Support for Pediatric Medication Adherence: Development and Feasibility Testing

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction We developed MedSupport, a multilevel medication adherence intervention designed to address root barriers to medication adherence. This study sought to explore the feasibility and acceptability of the MedSupport intervention strategies to support a future full‐scale randomized controlled trial.
Elizabeth G. Bouchard, Hital Patel, Paula C. Vincent, Justine Kahn, Kira Bona, Thai Hoa Tran, Elisa M. Rodriguez, Kristopher Attwood, Kara M. Kelly   +8 more
wiley   +1 more source

Mode of delivery does not have a relationship with high-risk HPV positivity

Clinical and Experimental Obstetrics & Gynecology, 2020
Objective: This study aims to evaluate the delivery room data for patients who give birth with standard vaginal delivery and caesarean section (C/S), to estimate whether high-risk (HR) HPV status affected the mode of delivery.
G. Sel, A. Barut, Ü. Özmen, A. Y. Akdemir, S. Harma, B. Aynalı, M. Harma, M.İ. Harma   +7 more
doaj   +1 more source

Stereotactic Body Radiation Therapy for Pediatric, Adolescent, and Young Adult Patients With Osteosarcoma: Local Control Outcomes With Dosimetric Analysis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background/Objectives Osteosarcoma is a radioresistant tumor that may benefit from stereotactic body radiation therapy (SBRT) for locoregional control in metastatic/recurrent disease. We report institutional practice patterns, outcomes, toxicity, and failures in osteosarcoma patients treated with SBRT.
Jenna Kocsis, Shauna R. Campbell, Jonathan Jang, Eashwar Somasundaram, Chandana A. Reddy, Jacob G. Scott, Lilyana Angelov, Peter M. Anderson, Matteo Trucco, Zachary Burke, Lukas Nystrom, Nathan Mesko, Anthony Magnelli, Erin S. Murphy   +13 more
wiley   +1 more source

DNA Vaccines: Their Formulations, Engineering and Delivery

Vaccines
The concept of DNA vaccination was introduced in the early 1990s. Since then, advancements in the augmentation of the immunogenicity of DNA vaccines have brought this technology to the market, especially in veterinary medicine, to prevent many diseases ...
Michael Kozak, Jiafen Hu
doaj   +1 more source