Results 131 to 140 of about 3,741,440 (311)
Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy
Molecular Oncology, EarlyView.LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir +9 more
wiley +1 more source
Public Health ChallengesBackground The double burden of malnutrition at household level (DBMHL), which denotes the coexistence of undernutrition and overweight or obesity within the same household, underscores the complex and multifaceted nature of malnutrition.
Maliha Mahazabin +2 more
doaj +1 more source
USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival
Molecular Oncology, EarlyView.CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna +8 more
wiley +1 more source
A Multicenter Retrospective Cohort Study of Pregnancy Outcomes in Idiopathic Oligohydramnios at Term
International Journal of Women's HealthHui Gao,1 Hui Tao,1 Li Zou,1 Qing-Qing Luo,1,2 Wei-Yuan Zhang3 1Department of Obstetrics and Gynecology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, People’s Republic of China; 2Department of Obstetrics ...
Gao H, Tao H, Zou L, Luo QQ, Zhang WY
doaj
Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
FEBS Open Bio, EarlyView.Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee +3 more
wiley +1 more source
Associations between mode of delivery and neonatal outcomes.
, 2017 Associations between mode of delivery and neonatal outcomes.
Lei Hou (274359) +6 more
core +1 more source
FEBS Open Bio, EarlyView.UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
Huli yanjiu, 2018 Objective:To analyze the hot spots and trends of midwifery specialty in china.Method:Data from CNKI,China Academic Journal Network Publishing total library 2006—2016 nearly 10 years of midwifery professional research literatures were selected,and ...
何菁菁, 罗碧如
doaj
Characteristics of the study population by mode of delivery.
, 2017 Characteristics of the study population by mode of delivery.
Lei Hou (274359) +6 more
core +1 more source
Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1
FEBS Open Bio, EarlyView.The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay +2 more
wiley +1 more source