Results 71 to 80 of about 1,161,993 (302)

Performance evaluation of MPEG-4 video streaming over UMTS networks using an integrated tool environment [PDF]

open access: yes, 2005
Universal Mobile Telecommunications System (UMTS) is a third-generation mobile communications system that supports wireless wideband multimedia applications.
Heijenk, Geert   +2 more
core   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

GESTATIONAL SARS-COV-2 AND THE MODE OFDELIVERY: MINIREVIEW

open access: yesTrakia Journal of Sciences
Purpose: The emergence of the SARS-CoV-2 coronavirus has posed untold challenges to medical systems, as pregnant women are more susceptible to its harmful effects.
R. S. Jasem Al-Dahwi   +2 more
doaj   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Seeding and feeding: nutrition and birth-associated exposures shape gut microbiome assembly in breastfed infants

open access: yesGut Microbes
Gut microbiome establishment in early life is influenced by maternal, infant, and environmental factors, with disruptions linked to later disease risk. Although infant diet is a major determinant of microbial composition, longitudinal data in breastfed ...
Lisa F. Stinson   +6 more
doaj   +1 more source

A simple integrated single-atom detector

open access: yes, 2009
We present a reliable and robust integrated fluorescence detector capable of detecting single atoms. The detector consists of a tapered lensed single-mode fiber for precise delivery of excitation light and a multimode fiber to collect the fluorescence ...
Abraham   +24 more
core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Eutocic delivery vs. cesarean section: a multicenter retrospective study of factors influencing cesarean rates in Robson groups 1, 2a, 3, and 4a across birth centers

open access: yesFrontiers in Medicine
ObjectiveCesarean deliveries are increasing rapidly worldwide. Although their primary indication is when vaginal delivery is not feasible, there appears to be an overutilization of this procedure, even in the absence of clear medical or obstetric ...
Alessandra Musicco   +7 more
doaj   +1 more source

Power converter [PDF]

open access: yes, 1981
A dc-to-dc converter employs four transistor switches in a bridge to chop dc power from a source, and a voltage multiplying diode rectifying ladder network to rectify and filter the chopped dc power for delivery to a load.
Black, J. M.
core   +1 more source

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