Results 131 to 140 of about 640,373 (307)

Optimizing the number and location of warehouses in logistics networks considering the optimal delivery routes and set level of reserve stock [PDF]

open access: yes, 2013
Forming the optimal structure of a warehouse network is one of the main strategic tasks in arranging an efficient logistics network. The suggested mathematical model and iterative method allow an optimal number and location of warehouses (in the area ...
Sysoiev, Volodymyr Viktorovych
core  

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Political economy of infrastructure spending in India [PDF]

open access: yes
This paper examines a puzzle in the political economy of infrastructure in India -- the co-existence of relatively low shares of capital spending in public budgets alongside evidence of large demand for village infrastructure from poor voters.
Khemani, Stuti
core  

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

VERIFICATION IN CONTRACTS WITH RANDOM CHANGES IN QUALITY [PDF]

open access: yes
Many goods and services are subject to random changes in quality during the time between sale and delivery, resulting in markets characterized by lemons-market equilibria.
Dimitri, Carolyn, Lichtenberg, Erik
core   +1 more source

Rating system in Food delivery [PDF]

open access: yes, 2017
A small business in food delivery has much competition. The organisation delivers food in food trucks at local markets. The aim of this research is to examine how a rating system will impact on the quality of goods and services and customer satisfaction ...
Lee, Rosie, Robertson, Jan
core  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

The delivery of goods in the city

open access: yes, 2013
Ce cas permet d’aborder le difficile et délicat problème de la distribution urbaine, à travers le transport des marchandises en ville, ce dernier concernant à la fois les livraisons des commerçants de proximité et celles des particuliers, notamment celles, de plus en plus nombreuses, des internautes.L’objet du cas est, avant tout, de présenter les ...
Durand, Bruno, Senkel, Marie-Pascale
openaire   +1 more source

Triangulation Framework for Local Service Delivery [PDF]

open access: yes, 2009
How should local service delivery of public goods and services be improved for desirable development outcomes? This paper attempts at answering this question by providing a framework for improving local service delivery.
Layug, Allan S.
core  

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

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