Results 11 to 20 of about 200 (133)
Large Igneous Provinces (LIPs) and Anoxia Events in “The Boring Billion”
Geophysical Monograph Series, Page 449-486., 2021 Exploring the links between Large Igneous Provinces and dramatic environmental impact
An emerging consensus suggests that Large Igneous Provinces (LIPs) and Silicic LIPs (SLIPs) are a significant driver of dramatic global environmental and biological changes, including mass extinctions.
Shuan‐Hong Zhang +4 more
wiley +2 more sources
All‐PEG‐Like Block Copolymers Self‐Assemble into Stealth Nanocarriers for Drug Delivery
Advanced Science, EarlyView.Self‐assembling nanoparticles composed entirely of POEGMA are engineered by exploiting side‐chain–dependent amphiphilicity and tunable thermoresponsive behavior. These single‐material nanocarriers encapsulate diverse hydrophobic drugs with high efficiency, retain therapeutic activity, improve in vivo efficacy, and evade anti‐PEG antibodies.
Parul Sirohi +15 more
wiley +1 more source
Advanced Energy Materials, EarlyView.P2‐type sodium layered oxides have potential for high‐voltage operation but suffer from structural instability and capacity fading. This work demonstrates that synergistic Li and Ti co‐doping enhances sodium inventory, suppresses detrimental phase transitions, and activates reversible lattice oxygen redox.
Rishika Jakhar +16 more
wiley +1 more source
Zoo Biology, EarlyView.We investigated the extent and composition of red panda (Ailurus Fulgens spp.) encounters amongst 150 global zoos and their impact on animal longevity and reproduction. Comparative data analysis suggests that encounter animals produced more offspring and had higher longevity (survival) than non‐encounter animals with differences noted between ...
Sarah L. Spooner +6 more
wiley +1 more source
Australian Journal of Agricultural and Resource Economics, EarlyView.ABSTRACT Resilience is still conceptualised as gender‐neutral in research and policy discussions. However, a gendered resilience framework suggests that gender roles and intra‐household dynamics are intricately linked with household resilience. This manuscript aims to analyse the effect of gender role attitudes on climate change resilience.
Bekhzod Egamberdiev +3 more
wiley +1 more source
Contested Memories in Stone: The Memorial Landscape of Waterloo Battlefield
Area, EarlyView.Short Abstract This article examines the Waterloo battlefield as a spatially contested memorial landscape shaped by competing national and transnational narratives. Through GIS mapping and inscription analysis, it demonstrates how spatial arrangements and commemorative rhetoric reproduce different narratives while enabling grassroots actors ...
Bowen Chai
wiley +1 more source
British Journal of Pharmacology, EarlyView.Background The activity of CYP2C9, an important drug metabolism enzyme, is subject to the impact of genetic polymorphism. The single nucleotide polymorphism *3 is significantly associated with the increased exposure of CYP2C9 substrates. In addition, metabolic enzyme inhibitors such as fluconazole may also increase the drug exposure of CYP2C9 ...
Shen Cheng +5 more
wiley +1 more source
Covalent drug discovery: Progress against key targets, emerging strategies and lessons learnt
British Journal of Pharmacology, EarlyView.Abstract Covalent drug discovery is currently experiencing a boom in industrial and academic interest. To date, at least 75 covalent drugs have received regulatory approval, targeting both traditional target classes and more challenging proteins for which other approaches failed. In many cases, unique aspects of covalent targeting are essential for the
Charles P. Brown +2 more
wiley +1 more source
Advancing conservation breeding programs for marine invertebrates
Conservation Biology, EarlyView.Abstract In the face of ecosystem change and biodiversity loss caused by climate change and other stressors, conservation breeding, or captive breeding, with the aim of reintroduction for wild population recovery, is an emerging tool for preventing species’ extinction and rehabilitating ecosystems.
Elora H. López‐Nandam +3 more
wiley +1 more source
Age‐specific melanoma risk associated with nevi: a pooled analysis from the M‐SKIP project
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.Summary Objective This study investigates the association of melanoma risk with total‐body nevus count and the presence of atypical nevi in younger (< 40 years) and older (> 60 years) individuals. Methods A pooled analysis was conducted within the M‐SKIP project, based on multiple melanoma case‐control studies.
Giulia Doi +20 more
wiley +1 more source