Results 111 to 120 of about 814,108 (379)
Protonation states are crucial for molecular recognition. Chemoinformatic tools often miss atypical protonation, hindering accurate drug design. Studies on the Endothiapepsin/PepstatinA complex reveal significant proton uptake upon ligand binding. A novel crystal structure together with ITC measurements and computational analyses pinpoint a pKa shift ...
Helge Vatheuer+5 more
wiley +1 more source
The application of the Delphi method in architectural research
Research in the field of architecture plays a significant role in the advancement of architectural knowledge and encourages architectural professionals to produce better architectural works.
Arman Arisman+2 more
doaj +1 more source
ESTIMATING THE INCIDENCE OF FOODBORNE SALMONELLA AND THE EFFECTIVENESS OF ALTERNATIVE CONTROL MEASURES [PDF]
Foodborne illness incidence, Salmonella, Delphi method, United Kingdom, Food Consumption/Nutrition/Food Safety,
Henson, Spencer J.
core +1 more source
Determining information for inclusion in a decision-support intervention for clinical trial participation : A modified Delphi approach [PDF]
Peer ...
Campbell, Marion K+4 more
core +1 more source
There is a scarcity of information related to the financial impact of acute kidney injury (AKI), and even more so the economics of drug‐associated AKI (D‐AKI). Our goal was to provide a comprehensive summary of the economic burden of D‐AKI by evaluating the costs of D‐AKI compared to not developing AKI and cost savings associated with nephrotoxin ...
Britney A. Stottlemyer+3 more
wiley +1 more source
Delphi method: oracle or sound judgment? [PDF]
In ancient Greece, Delphi was thought to be the very center of the world. According to the legend, when Apollo slew Python, his body fell into a fissure at the site of Delphi. Over this fissure sat the priestess Pythia, and the fumes that arose from his decomposing body, brought her into a trance, allowing her to prophesize.
openaire +3 more sources
Drug development is a lengthy process with considerable uncertainty at each milestone. Several trials are needed to progress to confirmatory evaluation and establish a positive benefit–risk balance. One of the critical milestones is the decision to progress to phase III based on phase II trial results. Use of probability of success is becoming standard
Aysun Cetinyurek Yavuz+11 more
wiley +1 more source
Assessing the Sustainable Transition in LSPs Industry
ABSTRACT The growing pressure on logistics service providers (LSPs) to achieve strong sustainability performance highlights the importance of aligning their practices with technological tools to support such endeavour. Given the significant effort required to implement sustainability measures in companies, it is crucial to focus on implementing these ...
Piera Centobelli
wiley +1 more source
The participation of lifeworld experts in Delphi processes: A reflection on method and practice
Delphi studies have established themselves in the health sciences as a means to systematically and, ideally, synthesize expert opinions into a consensus on concrete issues. As participatory health research increases in relevance, lifeworld experts (e.g.,
Marlen Niederberger, Marco Sonnberger
doaj
THE EFFECT OF SOCIAL REPUTATION ON RETENTION: DESIGNING A SOCIAL REAL-TIME DELPHI PLATFORM [PDF]
Forecasting with high uncertainty and long-time horizons still challenges researchers and practitioners. A widely adopted method in knowledge sharing and forecasting based on experts is the Delphi method and its offspring, the Real-Time Delphi. While the
Kloker, Simon+3 more
core +1 more source