Results 1 to 10 of about 77,339,877 (193)

Homologous and Heterologous Expression of Delta(12)-Desaturase in Mucor circinelloides Enhanced the Production of Linolenic Acid [PDF]

Molecules, 2022
Linolenic acid (LA) is gaining more interest within the scientific community. This is because it has a potential medical role in reducing the risk of inflammation, carcinogenesis, atherosclerosis and diabetes and is a valuable nutraceutical for human ...
Junhuan Yang, Xiuwen Wang, Hassan Mohamed, Shaoqi Li, Chen Wu, Wenyue Shi, Futing Xue, Sergio López-García, Yuanda Song   +8 more
doaj   +6 more sources

Morphological Changes and Strong Cytotoxicity in Yarrowia lipolytica by Overexpressing Delta-12-Desaturase [PDF]

Journal of Fungi
In this study, delta-12 desaturase was overexpressed in Yarrowia lipolytica using the single-copy integrative vector pINA1312 and multicopy integrative vector pINA1292, resulting in the engineered yeast strains 1312-12 and 1292-12, respectively.
Yufei Chang, Zhen Wang, Hequn Li, Wenrui Dang, Yuanda Song, Xinxin Kang, Huaiyuan Zhang   +6 more
doaj   +4 more sources

Improved γ-linolenic acid production in Mucor circinelloides by homologous overexpressing of delta-12 and delta-6 desaturases [PDF]

Microbial Cell Factories, 2017
Background γ-Linolenic acid (GLA) is important because of its nutritional value and medicinal applications. Although the biosynthetic pathways of some plant and microbial GLA have been deciphered, current understanding of the correlation between ...
Yao Zhang, Xiao Luan, Huaiyuan Zhang, Victoriano Garre, Yuanda Song, Colin Ratledge   +5 more
doaj   +5 more sources

Flaxseed Oil as a Source of Omega n-3 Fatty Acids to Improve Semen Quality from Livestock Animals: A Review

Animals, 2021
The demand to conserve indigenous species through the cryo-gene bank is increasing. Spermatozoa remain sensitive to cryopreservation damages especially that of avian species thus limiting the use of reproductive biotechnologies such as artificial ...
Jabulani Nkululeko Ngcobo, Fhulufhelo Vincent Ramukhithi, Khathutshelo Agree Nephawe, Takalani Judas Mpofu, Tlou Caswell Chokoe, Tshimangadzo Lucky Nedambale   +5 more
doaj   +1 more source

Variation of fatty acid desaturation in response to different nitrate levels in Auxenochlorella pyrenoidosa [PDF]

Royal Society Open Science, 2018
Microalgae are promising feedstocks for biodiesel, where the high proportion of monounsaturated fatty acid such as oleic acid (C18:1) is preferred. To regulate fatty acid desaturation in microalgae, the relationship among nitrate concentration, fatty ...
Qi Zhang, Zaizhi You, Xiaoling Miao
doaj   +1 more source

Effects of compound-326, a selective delta-5 desaturase inhibitor, in ApoE knockout mice with two different protocols for atherosclerosis development

Journal of Pharmacy & Pharmaceutical Sciences, 2021
Purpose: We previously confirmed its anti-atherosclerotic effects by pre-treatment with compound-326, a selective delta-5 desaturase (D5D) inhibitor, in Western diet-fed ApoE knockout mice.
Hiroki Nagase, Shuichi Takagahara, Yoshinori Satomi, Ayumi Ando, Kazuki Kubo, Shota Ikeda   +5 more
doaj   +1 more source

Comparative transcriptome analysis reveals ectopic delta-5 and delta-6 desaturases enhance protective gene expression upon Vibrio vulnificus challenge in Tilapia (Oreochromis niloticus)

BMC Genomics, 2021
Background Tilapia (Oreochromis niloticus) cultures are frequently infected by Vibrio vulnificus, causing major economic losses to production units. Previously, tilapia expressing recombinant delta-5 desaturase and delta-6 desaturase (D56) were found to ...
Pin-Yang Tu, Shin-Jie Huang, Venugopal Rajanbabu, Jen-Leih Wu, Jyh-Yih Chen   +4 more
doaj   +1 more source

Combining a Mutant Allele of FAD2-1A with HD Improves the ω-6/ω-3 Ratio in Soybeans

Agronomy, 2023
The intake of foods with unbalanced ω-6/ω-3 ratios causes various health problems. Commodity soybeans generally have a ω-6/ω-3 ratio of 6–7:1. The recommended ratio in terms of health benefits is
Hwayeop Kim, Hyun Jo, Jeong-Dong Lee
doaj   +1 more source

Dietary carbohydrate-to-protein ratio influences growth performance, hepatic health and dynamic of gut microbiota in atlantic salmon (Salmo salar)

Animal Nutrition, 2022
Atlantic salmon (Salmo salar) fed a carbohydrate-rich diet exhibit suboptimal growth performance, along with other metabolic disturbances. It is well known that gut microbes play a pivotal role in influencing metabolism of the host, and these microbes ...
Alejandro Villasante, Carolina Ramírez, Héctor Rodríguez, Patricio Dantagnan, Adrián Hernández, Elías Figueroa, Jaime Romero   +6 more
doaj   +1 more source

Up-regulated delta 9-desaturase gene expression by hypolipidemic peroxisome-proliferating fatty acids results in increased oleic acid content in liver and VLDL: accumulation of a delta 9-desaturated metabolite of tetradecylthioacetic acid

Journal of Lipid Research, 1997
In the liver of rats, monocarboxylic 3-thia fatty acids, tridecylthioacetic acid (C13-S-acetic acid) and tetradecylthioacetic acid (C14-S-acetic acid), increase the mRNA levels of delta 9-desaturase both in a time- and dose-dependent manner.
L Madsen, L Frøyland, H J Grav, R K Berge   +3 more
doaj   +1 more source