International Journal of Molecular Sciences, 2023 The regulation of microsomal (e.g., FAD2) and plastidial (e.g., FAD6) oleate desaturases by cold, heat and salt stress were investigated. Gene expression levels and fatty acid compositions were determined in the roots, stems and leaves of safflower following stress treatments. A safflower plastidial oleate desaturase gene, CtFAD6, was cloned, and oleic
Li, Dandan +3 more
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Eicosapentaenoic acid and 3,10 dithia stearic acid inhibit the desaturation of trans-vaccenic acid into cis-9, trans-11-conjugated linoleic acid through different pathways in Caco-2 and T84 cells. [PDF]
, 2006 Stearoyl-CoA desaturase (SCD) is a key enzyme that determines the composition and metabolic fate of ingested fatty acids, in particular the conversion of trans-vaccenic acid (TVA) to conjugated linoleic acid (CLA).
Renaville, B +23 more
core +1 more source
Development of marker-free transgenic
Biotechnology for Biofuels, 2012 Background Jatropha curcas is recognized as a new energy crop due to the presence of the high amount of oil in its seeds that can be converted into biodiesel.
Qu Jing +7 more
doaj +1 more source
Marine Drugs, 2019 The marine thraustochytrids are a promising source of docosahexaenoic acid (DHA) and the ketocarotenoid astaxanthin. In this study, the biosynthetic pathways of these two important metabolites in Aurantiochytrium sp.
Jingrun Ye +4 more
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Yeast Δ12 Fatty Acid Desaturase: Gene Cloning, Expression, and Function
Bioscience, Biotechnology, and Biochemistry, 2004 In an effort to elucidate the molecular mechanisms of fatty acid desaturation in yeast, a complete gene encoding Delta 12 fatty acid desaturase of Saccharomyces kluyveri was cloned. The open reading frame of this gene (named Sk-FAD2) consists of 1,251 bp, encoding 416 amino acids.
Kyoko Watanabe +3 more
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Both Determinants of Allosteric and Active Sites Responsible for Catalytic Activity of Delta 12 Fatty Acid Desaturase by Domain Swapping [PDF]
Enzyme and Microbial Technology, 2019 Abstract Cheese lacks essential fatty acids (EFAs). Delta 12 fatty acid desaturase ( FADS12 ) is a critical enzyme required for EFA biosynthesis in fermentation of the predominant strains of cheese.
Shi, Haisu +14 more
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The Journal of Poultry Science, 2013 This study was conducted to examine the effects of a combined in-feed supplementation of Aspergillus awamori and Saccharomyces cerevisiae on growth and muscle protein metabolism and fatty acid profiles in broilers.
Ahmed A. Saleh +2 more
doaj +1 more source
Low temperature and light regulate delta 12 fatty acid desaturases (FAD2) at a transcriptional level in cotton (Gossypium hirsutum) [PDF]
Journal of Experimental Botany, 2008 Lipid modifying enzymes play a key role in the development of cold stress tolerance in cold-resistant plants such as cereals. However, little is known about the role of the endogenous enzymes in cold-sensitive species such as cotton. Delta 12 fatty acid desaturases (FAD2), known to participate in adaptation to low temperatures through acyl chain ...
Kargiotidou, A. +4 more
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Abiotic Stresses and Phytohormones Regulate Expression of FAD2 Gene in Arabidopsis thaliana
Journal of Integrative Agriculture, 2012 Modification of unsaturated fatty acid (FA) levels has been found to accompany multiple abiotic stress acclimations in many plants. Delta 12 fatty acid desaturase (FAD2) plays a critical role in the synthesis of polyunsaturated FAs in plant cells by ...
Si-wei YUAN +4 more
doaj +1 more source
Cloning and functional analysis of the FAD2 gene family from desert shrub Artemisia sphaerocephala
BMC Plant Biology, 2019 Background Linoleic acid is an important polyunsaturated fatty acid, required for all eukaryotes. Microsomal delta-12 (Δ12) oleate desaturase (FAD2) is a key enzyme for linoleic acid biosynthesis. Desert shrub Artemisia sphaerocephala is rich in linoleic
Xiumei Miao +5 more
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