Results 141 to 150 of about 77,339,877 (193)

Engineering <i>Yarrowia lipolytica</i> for nervonic acid production by organelle compartmentalization and dynamic promoter coordination. [PDF]

Synth Syst Biotechnol
Ye S, He W, Yang N, He Q, Zhou J, Xia Y.
europepmc   +1 more source

Molecular Insights into the Functional Roles of Variants in the <italic>FADS</italic> Gene Cluster on Omega-3 Long-Chain Polyunsaturated Fatty Acid Synthesis.

Lifestyle Genom
Coulson M, Mutch DM.
europepmc   +1 more source

Study of the Δ12‐desaturase system ofLipomyces starkeyi

Lipids, 1996
AbstractThe specific activity of the microsomal Δ12‐desaturase system, which transforms oleic acid into linoleic acid, was about 16 pmol/min/mg protein. However, most of the total activity was nonsedimentable even after a 200000×g centrifugation for 100 min. The study of various physicochemical parameters showed that this enzymatic complex, functioning
Lomascolo, Anne, Dubreucq, Eric, Galzy, P.   +2 more
openaire   +3 more sources

Studies of the Δ12 desaturase of Carthamus tinctorius L

Archives of Biochemistry and Biophysics, 1985
The delta 12 desaturase of developing safflower seeds responsible for the conversion of an oleoyl moiety to the linoleoyl moiety of phospholipids was further characterized. The protein concentration of the microsomal preparation, the oleoyl-CoA concentration (the primary substrate), short incubation periods, and the addition of lysophospholipids must ...
J M, Gennity, P K, Stumpf
openaire   +2 more sources

Identification of conserved domains in the ?12 desaturases of cyanobacteria

Plant Molecular Biology, 1994
Cyanobacterial genes for enzymes that desaturate fatty acids at the delta 12 position, designated desA, were isolated from Synechocystis PCC6714, Synechococcus PCC7002 and Anabaena variabilis by cross-hybridization with a DNA probe derived from the desA gene of Synechocystis PCC6803.
T, Sakamoto, H, Wada, I, Nishida, M, Ohmori, N, Murata   +4 more
openaire   +2 more sources

Bioinformatics study of delta-12 fatty acid desaturase 2 (FAD2) gene in oilseeds

Molecular Biology Reports, 2014
Fatty acid desaturases constitute a group of enzymes that introduce double bonds into the hydrocarbon chains of fatty acids to produce unsaturated fatty acids. In plants, seed-specific delta-12 fatty acid desaturase 2 (FAD2) is responsible for the high content of linoleic acid by inserting a double bond at the delta-12 (omega-6) position of oleic acid.
Fatemeh, Dehghan Nayeri, Kazem, Yarizade
openaire   +2 more sources

Multiple Conserved Cysteine Residues Are Required for Delta‐12 Fatty Acid Desaturase Function in Arabidopsis thaliana

The FASEB Journal, 2022
Plants produce two essential fatty acids (FAs) for human nutrition: linoleic acid (18:2Δ 9,12 , an omega‐3 FA) and alpha‐linoleic acid (18:3Δ 9,12,15 , an omega‐6 FA). Plant FA desaturase 2 (FAD2) is a microsomal enzyme that introduces the carbon‐carbon
Lauren Novotny, Parth Dave, Patrick Horn
openaire   +1 more source

Fatty acid biosynthesis in eukaryotic photosynthetic microalgae: Identification of a microsomal delta 12 desaturase in Chlamydomonas reinhardtii

The Journal of Microbiology, 2008
Polyunsaturated fatty acids (PUFAs) are important components of infant and adult nutrition because they serve as structural elements of cell membranes. Fatty acid desaturases are responsible for the insertion of double bonds into pre-formed fatty acid chains in reactions that require oxygen and reducing equivalents.
Xiaoyuan, Chi, Xiaowen, Zhang, Xiangyu, Guan, Ling, Ding, Youxun, Li, Mingqing, Wang, Hanzhi, Lin, Song, Qin   +7 more
openaire   +2 more sources

Regio- and enantioselective oxidation of thiaoleic acids by an algal Δ12-desaturase

Phytochemistry, 1999
In a non aerated incubation medium, the oxidation of the tested thiaoleic acids by C. vulgaris was regioselective. Moreover the non oxidised 14-thiaoleic acid had no influence on the endogenous fatty acid pattern whereas the 13-thiaoleic acid, readily oxidised by the microalgae, caused a significant 18:1 accumulation in phospholipids.
L, Fauconnot, C, Nugier-Chauvin, N, Noiret, S, Poulain, H, Patin   +4 more
openaire   +2 more sources

An insect with a delta-12 desaturase, the jewel wasp Nasonia vitripennis, benefits from nutritional supply with linoleic acid

The Science of Nature, 2016
The availability of linoleic acid (LA; C18:2(∆9,12)) is pivotal for animals. While vertebrates depend on a nutritional supply, some invertebrates, including the parasitic wasp Nasonia vitripennis, are able to synthesize LA from oleic acid (OA; C18:1(∆9)).
Birgit, Brandstetter, Joachim, Ruther
openaire   +2 more sources