Results 31 to 40 of about 83,817 (262)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Computationally efficient low-power sigma delta modulation-based image processing algorithm

open access: yesMehran University Research Journal of Engineering and Technology, 2023
Digital Image Processing has dominated Digital Signal Processing at the cost of more memory, resources, and high computational power. In image processing, filtering transformations and other operations need complex multiplications, and the multiplier is ...
Aneela Pathan   +3 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Performance Scrutiny of Two Control Schemes Based on DSM and HB in Active Power Filter [PDF]

open access: yesJournal of Operation and Automation in Power Engineering, 2014
This paper presents a comparative analysis between two current control strategies, constant source power and generalized Fryze current, used in Active Power Filter (APF) applications having three different modulation methods. The Hysteresis Band (HB) and
R. Kazemzadeh   +3 more
doaj  

DOUBLE-DELTA-WINDING SYSTEM WITH NEUTRAL-POINT-CLAMPED CONVERTERS CONTROLLED BY SYNCHRONOUS MULTI-ZONE PWM

open access: yesПраці Інституту електродинаміки Національної академії наук України, 2020
In this paper, algorithms of the universal scheme of synchronous multi-zone modulation have been developed and dis-seminated for adjustment of two neutral-clamped inverters of double-delta-winding system (which is perspective for ap-plication in high ...
V. Oleschuk, V. Ermuratskii
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Transcranial alternating current stimulation in the theta band but not in the delta band modulates the comprehension of naturalistic speech in noise

open access: yesNeuroImage, 2020
Auditory cortical activity entrains to speech rhythms and has been proposed as a mechanism for online speech processing. In particular, neural activity in the theta frequency band (4–8 ​Hz) tracks the onset of syllables which may aid the parsing of a ...
Mahmoud Keshavarzi   +3 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Comparative Study between Duty Cycle Modulation (DCM) and Sigma-Delta (Ʃ∆) Modulation Based on Analog to Digital Conversion [PDF]

open access: yesJournal of Electrical and Electronics Engineering, 2023
This paper presents a virtual comparative study between the Analog to Digital Conversion (ADC) based Duty Cycle Modulation (DCM) and Sigma-Delta (Ʃ∆) modulation.
OTAM Steve Ulriche, MOFFO Lonla Bertrand
doaj  

High Frequency Pulse Width Modulation Converters [PDF]

open access: yesKirkuk Journal of Science, 2013
The delta modulation technique permits an accurate of an arbitrary reference. Spectrum of the current going through an inductive load shows a very low THD.
Ahmed Hassan Mohammed
doaj   +1 more source

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