Results 11 to 20 of about 1,674 (144)

North American Big Brown Bats (Eptesicus fuscus) Harbor an Exogenous Deltaretrovirus

mSphere, 2020
Bats are the reservoir for a large number of zoonotic viruses, including members of Coronaviridae (severe acute respiratory syndrome coronavirus [SARS-CoV] and SARS-CoV-2), Paramyxoviridae (Hendra and Nipah viruses), Rhabdoviridae (rabies virus), and ...
Ben M. Hause, Eric A. Nelson, Jane Christopher-Hennings   +2 more
doaj   +3 more sources

Deltaretroviruses have circulated since at least the Paleogene and infected a broad range of mammalian species [PDF]

Retrovirology, 2019
The Deltaretrovirus genus of retroviruses (family Retroviridae) includes the human T cell leukemia viruses and bovine leukemia virus (BLV). Relatively little is known about the biology and evolution of these viruses, because only a few species have been ...
Tomáš Hron, Daniel Elleder, Robert J. Gifford   +2 more
doaj   +2 more sources

Detection of Bovine Leukemia Virus in Argentine, Bolivian, Paraguayan and Cuban Native Cattle Using a Quantitative Real-Time PCR Assay-BLV-CoCoMo-qPCR-2 [PDF]

Pathogens
Bovine leukemia virus (BLV), an oncogenic retrovirus of the genus Deltaretrovirus, causes enzootic bovine leukosis (EBL), the most prevalent neoplastic disease in cattle and a major source of economic loss.
Guillermo Giovambattista, Aronggaowa Bao, Olivia Marcuzzi, Ariel Loza Vega, Juan Antonio Pereira Rico, Maria Florencia Ortega Masague, Liz Aurora Castro Rojas, Ruben Dario Martinez, Odalys Uffo Reinosa, Yoko Aida   +9 more
doaj   +2 more sources

Seroprevalence and Presumed Bovine Leukaemia Virus and Coxiella burnetii Coinfections in Three Dairy Cattle Herds From the Al Ain Region, United Arab Emirates. [PDF]

Vet Med Sci
ABSTRACT Background Bovine leukaemia virus (BLV) and Coxiella burnetii are important infectious pathogens of dairy cattle with potential implications for animal health, productivity and zoonotic transmission (in the case of C. burnetii). Because BLV may alter immune function, we hypothesize that infection with the virus could increase cattle ...
Barigye R, Hassan NA, Antony A, Zewude A, Abdalla-Alfaki IM, Alawadhi OAM, Amer AAA, Binsumaida MSN, Alshamsi MSS, Alderei HSH, Al Kalbani MS, Bensalah OK, Alnaqbi SA, Ameni G.   +13 more
europepmc   +2 more sources

Virus de la leucemia bovina: entre la producción animal y la salud humana

Revista Mvz Cordoba, 2023
El virus de la leucemia bovina (BLV) es un retrovirus del género deltaretrovirus, el cual infecta los linfocitos B y genera una expansión policlonal. En los rumiantes se integra como provirus al genoma del huésped y genera una infección de por vida.
Daniela Paternina B, Marco González T, Salim Mattar V   +2 more
doaj   +2 more sources

Different Mutation Tolerance of Lentiviral (HIV-1) and Deltaretroviral (BLV and HTLV) Protease Precursors

Viruses, 2022
The bovine leukemia virus (BLV) and the human T-lymphothropic viruses (HTLVs) are members of the deltaretrovirus genus of Retroviridae family. An essential event of the retroviral life cycle is the processing of the polyproteins by the viral protease (PR)
János András Mótyán, Norbert Kassay, Krisztina Matúz, József Tőzsér   +3 more
doaj   +2 more sources

Stage-Dependent Transcriptional Reprogramming of B-Cell Receptor Signaling and Antigen Presentation During Bovine Leukemia Virus-Driven Lymphomagenesis. [PDF]

Anim Genet
ABSTRACT Bovine leukemia virus (BLV), an oncogenic deltaretrovirus, establishes lifelong infection in cattle and induces enzootic bovine leukosis in a subset of animals following prolonged latency. Despite extensive evidence of immune dysregulation, stage‐specific transcriptional reprogramming of B cells, the primary viral reservoir remains ...
Akbarin MM, Farjami Z, Murillo CR, González-Fernández VD, Acevedo-Jiménez GE, de María Ávila-De la Vega L, Álvarez HR.   +6 more
europepmc   +2 more sources

No genetic evidence for involvement of Deltaretroviruses in adult patients with precursor and mature T-cell neoplasms [PDF]

Retrovirology, 2007
Background The Deltaretrovirus genus comprises viruses that infect humans (HTLV), various simian species (STLV) and cattle (BLV). HTLV-I is the main causative agent in adult T-cell leukemia in endemic areas and some of the simian T-cell lymphotropic ...
Hoelzer Dieter, Hummel Michael, Schwartz Stefan, Burmeister Thomas, Thiel Eckhard   +4 more
doaj   +2 more sources

Structural basis for the inhibition of HTLV-1 integration inferred from cryo-EM deltaretroviral intasome structures [PDF]

Nature Communications, 2021
Human T-cell lymphotropic virus type 1 (HTLV-1) is an oncogenic deltaretrovirus. Here the authors provide structural characterization of the binding mechanism of novel integrase strand transfer inhibitor (INSTI) candidates to limit HTLV-1 infection.
Michal S. Barski, Teresa Vanzo, Xue Zhi Zhao, Steven J. Smith, Allison Ballandras-Colas, Nora B. Cronin, Valerie E. Pye, Stephen H. Hughes, Terrence R. Burke, Peter Cherepanov, Goedele N. Maertens   +10 more
doaj   +2 more sources

Comparison of the Prevalence of Bovine Leukemia Virus (BLV) in Holstein and Angus Cattle Breeds From Shandong Province, China. [PDF]

Microbiol Immunol
ABSTRACT Bovine leukemia virus (BLV) is widespread globally and causes economic losses in the cattle industry. Shandong Province plays a significant role in China's livestock industry, with an increasing importance in food of Holstein and Angus cattle. However, BLV prevalence in Holstein and Angus breeds in Shandong Province remains unclear.
Wang J, Dong L, Guo G, Yao C, Wang C, Tian F, Wei F, Liu J, Wang X, Matsuura R, Watanuki S, Matsumoto Y, Wang J, Aida Y.   +13 more
europepmc   +2 more sources