Results 21 to 30 of about 5,667 (250)

Therapeutic Apheresis in Nigeria: A Multi‐Center Summary of Abstracts From the Inaugural Nigerian Society for Apheresis Scientific Meeting

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Therapeutic apheresis (TA) is an established treatment modality for hematologic, neurologic, and immunologic disorders, yet access remains severely limited in sub‐Saharan Africa. Donor apheresis, including platelet apheresis collection from healthy donors, represents an important complementary modality supporting blood product ...
Nosa Bazuaye   +33 more
wiley   +1 more source

After the Deluge: Central American Historiography at Low Tide

open access: yesLatin American Research Review, 2020
This essay reviews the following works:   Centroamérica: Filibusteros, estados, imperios y memorias. By Víctor Hugo Acuña. San José, Costa Rica: Editorial Costa Rica, 2014. Pp. xv + 151. $5.99 paperback. ISBN: 9789968684408.
Robert H. Holden
doaj   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Mechanisms of Devils Lake’s responses to recent climatic wetting: Insights from a physically based hydrologic model

open access: yesJournal of Hydrology: Regional Studies
Study region: Devils Lake Basin of the Northern Great Plains (NGP) region, North Dakota, USA Study focus: Understanding the mechanism of Devils Lake’s responses and basin-wide hydrologic change under a wet-climatic regime using a process-based and cold ...
Michaela L. Neal   +8 more
doaj   +1 more source

Visual Genome Explorer™: A Comparative Visual Interface to Genome Data

open access: yesBioTechniques, 1997
In response to the deluge of genome data, we are developing Visual Genome Explorer™, an interactive graphical interface to genome data. Given is a description of the prototype program, which introduces the concept of visual comparative genomics for ...
E. Scott Archer   +2 more
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

Investigation on relationship between tree rings of Cupressus sempervirens l . var . horizantalis and climatic variables [PDF]

open access: yesتحقیقات علوم چوب و کاغذ ایران, 2012
During 2008, a severe deluge in Sari caused huge damages and Cupressus sempervirens l. var. horizantalis trees in botany garden of Natural Sciences College were also fallen by the overflow.
Mahmood Kazemi   +2 more
doaj   +1 more source

Selective elimination of quiescent cancer cells by dequalinium chloride via ROS‐mediated ferroptosis

open access: yesFEBS Open Bio, EarlyView.
Dequalinium chloride (DQ) selectively eliminates quiescent cancer cells (QCCs) by amplifying mitochondrial ROS. QCCs exhibit elevated basal ROS and limited redox‐buffering capacity, making them vulnerable to further ROS increases. DQ‐induced ROS exceeds the tolerance threshold, triggering lipid peroxidation and ferroptosis, whereas proliferating cells ...
Kotaro Miyamoto   +14 more
wiley   +1 more source

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