Results 21 to 30 of about 5,667 (250)
ABSTRACT Background Therapeutic apheresis (TA) is an established treatment modality for hematologic, neurologic, and immunologic disorders, yet access remains severely limited in sub‐Saharan Africa. Donor apheresis, including platelet apheresis collection from healthy donors, represents an important complementary modality supporting blood product ...
Nosa Bazuaye +33 more
wiley +1 more source
After the Deluge: Central American Historiography at Low Tide
This essay reviews the following works: Centroamérica: Filibusteros, estados, imperios y memorias. By Víctor Hugo Acuña. San José, Costa Rica: Editorial Costa Rica, 2014. Pp. xv + 151. $5.99 paperback. ISBN: 9789968684408.
Robert H. Holden
doaj +1 more source
The microbiome in human skin aging
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Study region: Devils Lake Basin of the Northern Great Plains (NGP) region, North Dakota, USA Study focus: Understanding the mechanism of Devils Lake’s responses and basin-wide hydrologic change under a wet-climatic regime using a process-based and cold ...
Michaela L. Neal +8 more
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Visual Genome Explorer™: A Comparative Visual Interface to Genome Data
In response to the deluge of genome data, we are developing Visual Genome Explorer™, an interactive graphical interface to genome data. Given is a description of the prototype program, which introduces the concept of visual comparative genomics for ...
E. Scott Archer +2 more
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Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks +4 more
wiley +1 more source
Investigation on relationship between tree rings of Cupressus sempervirens l . var . horizantalis and climatic variables [PDF]
During 2008, a severe deluge in Sari caused huge damages and Cupressus sempervirens l. var. horizantalis trees in botany garden of Natural Sciences College were also fallen by the overflow.
Mahmood Kazemi +2 more
doaj +1 more source
Selective elimination of quiescent cancer cells by dequalinium chloride via ROS‐mediated ferroptosis
Dequalinium chloride (DQ) selectively eliminates quiescent cancer cells (QCCs) by amplifying mitochondrial ROS. QCCs exhibit elevated basal ROS and limited redox‐buffering capacity, making them vulnerable to further ROS increases. DQ‐induced ROS exceeds the tolerance threshold, triggering lipid peroxidation and ferroptosis, whereas proliferating cells ...
Kotaro Miyamoto +14 more
wiley +1 more source

