Results 31 to 40 of about 85,013 (191)

A Transcriptome‐Wide Mendelian Randomization Study in Isolated Human Immune Cells Highlights Risk Genes Involved in Viral Infections and Potential Drug Repurposing Opportunities for Schizophrenia

open access: yesAmerican Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT Schizophrenia is a neurodevelopmental psychiatric disorder characterized by symptoms of psychosis, thought disorder, and flattened affect. Immune mechanisms are associated with schizophrenia, though the precise nature of this relationship (causal, correlated, consequential) and the mechanisms involved are not fully understood.
David Stacey   +6 more
wiley   +1 more source

Psychic embedding — vision and delusion [PDF]

open access: yes, 2008
The paper introduces the idea that the human brain may apply complex mathematical modules in order to process and understand the world. We speculate that the substrate of what appears outwardly as intuition, or prophetic power, may be a mathematical ...
Radulescu, Anca
core  

Alzheimer's Association clinical practice guideline for the Diagnostic Evaluation, Testing, Counseling, and Disclosure of Suspected Alzheimer's Disease and Related Disorders (DETeCD‐ADRD): Executive summary of recommendations for primary care

open access: yesAlzheimer's &Dementia, EarlyView.
Abstract US clinical practice guidelines for the diagnostic evaluation of cognitive impairment due to Alzheimer's disease (AD) or AD and related dementias (ADRD) are decades old and aimed at specialists. This evidence‐based guideline was developed to empower all—including primary care—clinicians to implement a structured approach for evaluating a ...
Alireza Atri   +10 more
wiley   +1 more source

Does reject inference really improve the performance of application scoring models? [PDF]

open access: yes, 2004
The voter model on Zd is a particle system that serves as a rough model for changes of opinions among social agents or, alternatively, competition between biological species occupying space.
Banasik, John, Crook, Jonathan
core   +3 more sources

Psychoses of Epilepsy: Unravelling the Phenotypic and Genotypic Features

open access: yesAnnals of Neurology, EarlyView.
Objectives We analyzed the genotypic and phenotypic features of patients with psychosis of epilepsy (POE). Methods Patients with POE recruited to an epilepsy genetics research program underwent phenotyping and genetic analysis. The latter included screening for rare pathogenic variants in epilepsy genes, and polygenic risk score (PRS) calculation for ...
Genevieve Rayner   +4 more
wiley   +1 more source

Myth about neuronal nitric oxide synthase in the sarcolemma of skeletal muscles [PDF]

open access: yes, 2008
In skeletal muscles, neuronal NO synthase (nNOS, designated also as NOS1) was reported to be restricted to the sarcolemma. With the advent of modern powerful immunocytochemical techniques this commonly accepted view appears to be a delusion and has to be
Igor Buchwalow, Werner Boecker
core   +1 more source

AI in Neurology: Everything, Everywhere, all at Once PART 2: Speech, Sentience, Scruples, and Service

open access: yesAnnals of Neurology, EarlyView.
Artificial intelligence (AI) applications are finding use in real‐world neurological settings. Whereas part 1 of this 3‐part review series focused on the birth of AI and its foundational principles, this part 2 review shifts gears to explore more practical aspects of neurological care.
Matthew Rizzo
wiley   +1 more source

Cholinergic Degeneration and Cognitive Function in Early GBA1‐Related Parkinson's Disease

open access: yesAnnals of Neurology, EarlyView.
Objective The phenotype of patients with Parkinson's disease carrying GBA1 variants (GBA‐PD) suggest similarities to symptomatology associated with early cholinergic system degeneration. Therefore, this study aims to investigate the clinical features and the cholinergic innervation pattern in patients with early GBA‐PD versus those without the GBA1 ...
Sofie Slingerland   +6 more
wiley   +1 more source

Sleep Deprivation and Delusion Proneness: Influence on Dream Bizarreness [PDF]

open access: yes, 2012
While evidence for many types of psychotic experience exists in the general population, dreams have been a particularly prominent model for hallucinations and delusions in otherwise healthy individuals.
Lezon, Anna Leigh
core   +1 more source

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