Results 151 to 160 of about 123,697 (304)

Pharmacokinetics and pharmacodynamics of intravenous and oral (S)‐ketamine: Investigating metabolite contribution to subjective effects

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Oral administration of (S)‐ketamine for treatment‐resistant depression (TRD), as alternative to the registered intranasal or off‐label intravenous administrations, has high potential. However, it is characterized by an extensive first‐pass metabolism, resulting in low (S)‐ketamine exposure and high levels of active metabolites, including (S ...
Marije E. Otto   +5 more
wiley   +1 more source

ASUHAN KEPERAWATAN PADA Tn. F DENGAN DIAGNOSA SKIZOFRENIA PARANOID DI UPT. REHABILITASI BINA LARAS PASURUAN [PDF]

open access: yes
Background: Schizophrenia is a type of mental disorder that is common and chronic,experienced for years, where there are difficulties with functional psychosis with major disturbances in thought processes, affect or emotions, volition and psychomotor ...
Monica, Agnes
core  

Psychotropic medication use among community dwellers with and without Parkinson's disease – A nationwide cohort study

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aims We studied the prevalence of psychotropic use and psychotropic polypharmacy in persons with Parkinson's disease (PD) during a 10‐year follow‐up, because longitudinal studies on this topic are scarce although non‐motor symptoms of PD are often treated with psychotropics.
Noora Nieminen   +4 more
wiley   +1 more source

Exploring new avenues: Psychedelic‐assisted therapy for young people

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Rates of mental illness in young people are increasing, whereas the development of novel mental health treatments has not significantly progressed. Psychedelic‐assisted therapy, using substances such as psilocybin and 3,4‐methylenedioxymethamphetamine (MDMA), has shown potential in the treatment of mental illnesses in the adult population, including ...
Ioanna Artemis Vamvakopoulou   +3 more
wiley   +1 more source

Serotonin 5‐HT7 receptor signaling in neuropsychiatric disorders

open access: yesBulletin of the Korean Chemical Society, EarlyView.
5‐HT7R recruits Gs, G12, and β‐arrestin signaling to regulate neuronal plasticity, circuit function, and kinase‐linked intracellular responses. This review summarizes how these pathway‐selective modules contribute to autism spectrum disorder, depression, and schizophrenia, highlighting 5‐HT7R as a pathway‐informed therapeutic target. Abstract Serotonin
Eunseo Park, Hyunah Choo
wiley   +1 more source

Green Is the New Gold: Redefining Opulent Lifestyle Through Organic Food Purchases

open access: yesBusiness Strategy and the Environment, EarlyView.
ABSTRACT Prior studies based on the Theory of Planned Behavior mostly examined the effects of health and environmental concerns on organic food consumption; however, few addressed the paradoxical relationships in the context of opulent or symbolic decorum.
Neha Sharma   +3 more
wiley   +1 more source

Innovating for Net‐Zero: Collaborative and Digital Decarbonisation Strategies in Sunset Industries' Global Value Chains

open access: yesBusiness Strategy and the Environment, EarlyView.
ABSTRACT Global net‐zero ambitions require transformative strategies to decarbonise carbon‐intensive global value chains (GVCs). This study examines how multinational enterprises (MNEs) in sunset industries integrate carbon capture technologies (CCT) with operational and supply chain dynamics (OSCD) to advance decarbonisation.
Muhammad Mustafa Kamal   +6 more
wiley   +1 more source

Consumer Acceptance of Conversational Bots: Systematic Literature Review and Meta‐Analysis

open access: yesJournal of Consumer Behaviour, EarlyView.
ABSTRACT As consumers increasingly rely on conversational bots for daily tasks, evidence surrounding motivations for acceptance remains scattered. A systematic literature review (SLR) was conducted on 64 journal articles published between 2008 and 2024, of which 48 provided sufficient quantitative data for inclusion in a meta‐analysis.
Omar H. Fares, Seung Hwan (Mark) Lee
wiley   +1 more source

The Lived Experience of Delirium in a Critically Ill Child: A Narrative Study. [PDF]

open access: yesScand J Caring Sci
Stenkjaer RL   +4 more
europepmc   +1 more source

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