Results 131 to 140 of about 17,023 (259)
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Evaluating the Dynamic Employment Effects of Training Programs in East Germany Using Conditional Difference–in–Differences [PDF]
, 2004 This paper evaluates the effects of Public Sponsored Training in East Germany in the context of reiterated treatments. Selection bias based on observed characteristics is corrected for by applying kernel matching based on the propensity score. We control
Speckesser, Stefan +2 more
core
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
The Effect of Early Mobilization for the Patients of Chronic Subdural Hematoma after Closed Drainage Surgery. [PDF]
, 2010 OBJECTIVE: The purpose of this study is to evaluate the effect of early mobilization for the patients of chronic subdural hematoma after closed drainage.
정현호
core
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Bathymetric DEM of Difference (DoD) of "Afryka" reservoir 2020-2023 (Lubuskie, Western Poland)
The file contains the Digital Terrain Model difference (DoD) raster of the "Afryka" reservoir of the old "Przyjaźń Narodów - Szyb Babina" lignite mine in western Poland (Lubuskie) bathymetric data.
Wajs, Jaroslaw
core +1 more source
EVALUATION OF ACCURACY OF DEMS OBTAINED FROM UAV-POINT CLOUDS FOR DIFFERENT TOPOGRAPHICAL AREAS
International Journal of Engineering and Geosciences, 2017 The main objective of the study was to examine accuracies of DEMs (Digital Elevation Models) with different topographical structures generated by using the Unmanned Aerial Vehicle (UAV) point clouds. Two different terrains with flat and sloping topographical structures were selected for the study, and DEMs of these terrains were generated using eight ...
openaire +4 more sources
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
FEBS Letters, EarlyView.The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source