Results 31 to 40 of about 4,096 (261)

A survey of research on demand responsive transit and its route optimization

open access: yes智能科学与技术学报, 2021
With the widespread application of new infrastructure and other technologies, demand responsive transit (DRT) is becoming the trend of urban traffic development in the future.In order to further clarify the research status of DRT at home and abroad ...
Shuai FENG, Xiaoming LIU
doaj  

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Designing High-Freedom Responsive Feeder Transit System with Multitype Vehicles

open access: yesJournal of Advanced Transportation, 2020
The last mile travelling problem is the most challenging part when using public transit. This study designs a high-freedom responsive feeder transit (HFRFT) system to serve at the transfer station, given vehicle routes, departure time, and service area ...
Zhengwu Wang   +4 more
doaj   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

An optimized two‐phase demand‐responsive transit scheduling model considering dynamic demand

open access: yesIET Intelligent Transport Systems
Demand‐responsive transit has gradually attracted attention in recent years for its flexibility, efficiency, and ability to meet the diverse travel demands of passengers.
Cui‐Ying Song   +3 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Vehicle scheduling optimization for demand responsive transit with flexible stops

open access: yesShenzhen Daxue xuebao. Ligong ban
Flexible stops demand responsive transit is a public transportation mode that combines fixed service stops with the ability for passengers to book at flexible stops.
SHEN Zikang, JIN Wenzhou, ZHENG Yajing
doaj   +1 more source

Personalised and Coordinated Demand-Responsive Feeder Transit Service Design: A Genetic Algorithms Approach

open access: yesFuture Internet, 2018
The purpose of this work is to create an efficient optimization framework for demand-responsive feeder transit services to assign vehicles to cover all pickup locations to transport passengers to a rail station.
Bo Sun   +4 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Improving demand responsive transit services: Insights from the London field test

open access: yesJournal of Public Transportation
The paper discusses the key insights gained from “GoSutton”, a Demand Responsive Transit (DRT) trial in the borough of Sutton in the suburbs of London during 2019–2020.
Seyedmostafa Zahedi   +2 more
doaj   +1 more source

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