Results 61 to 70 of about 112,022 (343)

Efficacy and Tolerability of Topotecan/Cyclophosphamide/Dinutuximab in Relapsed and Refractory High‐Risk Neuroblastoma: A Multi‐Institutional Retrospective Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Chemoimmunotherapy with irinotecan, temozolomide, and dinutuximab (I/T/DIN) has emerged as first‐line therapy for relapsed/refractory (r/r) high‐risk neuroblastoma (HRNB) in North America. Topotecan and cyclophosphamide (T/C) are often used in combination with dinutuximab in the setting of lack of response, progression, or incomplete ...
Benjamin J. Lerman   +17 more
wiley   +1 more source

Strategic Planning and Prospects of Rail-Bound Demand Responsive Transit [PDF]

open access: yesTransportation Research Record: Journal of the Transportation Research Board, 2018
Fully automated services allow for greater flexibility in operations and lower marginal operational costs. In this study we examined the strategic planning implications of a novel service concept – an automated rail demand responsive transit (DRT) system that offers a direct non-stop service.
Cats, Oded, Haverkamp, Jesper
openaire   +4 more sources

Case studies of job access and reverse commute program: 2009-2010 [PDF]

open access: yes, 2011
This report presents perceptual, mobility and employment outcomes self-reported by 573 users of 26 transportation services funded by the Job Access and Reverse Commute (JARC) program.
Blaise, E.T.   +5 more
core  

Unique Opportunities of Island States to Transition to a Low-Carbon Mobility System [PDF]

open access: yes, 2020
Small islands developing states (SIDS) contribute minuscule proportions to global greenhouse gas (GHG) emissions and energy consumption, but are highly exposed to climate change impacts, in particular to extreme weather events and sea-level rise. However,
Blechinger, Philipp   +2 more
core   +1 more source

Treatment Decision‐Making Roles and Preferences Among Adolescents and Young Adults With Cancer

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Decision‐making (DM) dynamics between adolescents and young adults (AYAs) with cancer, parents, and oncologists remain underexplored in diverse populations. We examined cancer treatment DM preferences among an ethnically and socioeconomically diverse group of AYAs and their parents.
Amanda M. Gutierrez   +14 more
wiley   +1 more source

Optimizing Multi-Terminal Customized Bus Service With Mixed Fleet

open access: yesIEEE Access, 2020
The customized bus (CB) transit is recognized as an effective transportation mode offering more flexible and demand-responsive service than traditional bus transit with fixed route and schedule, especially during the peak hours. The novelty of this study
Qian Sun   +4 more
doaj   +1 more source

Upacicalcet: A Novel Intravenous Calcimimetic Agent for Patients Undergoing Hemodialysis With Secondary Hyperparathyroidism

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Secondary hyperparathyroidism (SHPT) is a common complication in patients receiving maintenance dialysis, driven by calcium and phosphate metabolism disturbances. Calcimimetics are central to the management of SHPT by enhancing calcium‐sensing receptor sensitivity and reducing parathyroid hormone secretion.
Fumihiko Koiwa   +3 more
wiley   +1 more source

Performance analysis and fleet requirements of automated demand-responsive transport systems as an urban public transport service

open access: yesInternational Journal of Transportation Science and Technology, 2018
The introduction of public transport services by fully automated vehicles can potentially change the way public transit services will be operated, as they allow shifting from rigid scheduled and route-bound services towards flexible, demand-responsive ...
Konstanze Winter   +3 more
doaj   +1 more source

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

open access: yesFEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Economies in U.S. demand responsive transit

open access: yesJournal of Advanced Transportation, 1987
AbstractThis paper develops a neoclassical cost function for demand responsive transit (DRT) system and uses it to test the economies of scale hypothesis. The results show economies of scale and further show that the economies can be explained by speed, local and state subsidies, utilization of seating capacity, fleet utilization and an increase in the
openaire   +1 more source

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