Results 61 to 70 of about 63,983 (304)

Is sea-basing a viable method of providing logistic support to the UK amphibious force? [PDF]

open access: yes, 2000
Maritime power has traditionally been a central part of the UK’s defence planning and is well suited to supporting a wide range of military operations. The littoral area has always created problems for naval planners as most landings historically have ...
Antill, Peter D.   +2 more
core  

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Feeding Urban Rail Transit: Hybrid Microtransit Network Design Based on Parsimonious Continuum Approach

open access: yesInformation
In recent years, the passenger flow volume of conventional transit in major cities has declined steadily. Ground public transit often suffers from congestion during rush hours caused by frequent stops (e.g., conventional fixed-route buses) or excessively
Qian Ye   +4 more
doaj   +1 more source

Economies in U.S. demand responsive transit

open access: yesJournal of Advanced Transportation, 1987
AbstractThis paper develops a neoclassical cost function for demand responsive transit (DRT) system and uses it to test the economies of scale hypothesis. The results show economies of scale and further show that the economies can be explained by speed, local and state subsidies, utilization of seating capacity, fleet utilization and an increase in the
openaire   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Iterated clustering optimization of the split-delivery vehicle routing problem considering passenger walking distance

open access: yesTransportation Research Interdisciplinary Perspectives, 2023
The user-oriented, demand-driven nature of customized shuttle bus (CSB) services forces operators to pay more attention to service quality. However, the bus route planning of CSB and other similar systems in established studies rarely took service ...
Jiangbo Wang   +3 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Why do demand responsive transport systems fail? [PDF]

open access: yes, 2006
In developed countries, Demand Responsive Transport (DRT) (loosely termed 'paratransit' in US parlance) emerged in the 1970s to serve the specialist niche market of people with mobility difficulties.
Enoch, Marcus   +3 more
core  

Future prospects for personal security in travel by public transport [PDF]

open access: yes, 2014
This work was supported by the Engineering and Physical Sciences Research Council [grant number EP/I037032/1].
Beecroft, Mark, Pangbourne, Kate
core   +2 more sources

Personalized Demand-Responsive Transit Service [PDF]

open access: yes, 2004
Providing easy access to the public transit service is the goal of the California transit agencies. Many travelers cannot take an express transit because they often cannot park and ride. Smart DRT (demand responsive transit) Feeder is a system that collects transit riders from neighborhoods and takes them to transit stations. This system will use APTS (
Cayford, Randall, Yim, Y. B. Youngbin
openaire   +1 more source

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