Results 71 to 80 of about 112,022 (343)

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Integrated Modeling Approach for the Transportation Disadvantaged [PDF]

, 2007
Transportation models have not been adequate in addressing severe long-term urban transportation problems that transportation disadvantaged groups overwhelmingly encounter, and the negative impacts of transportation on the disadvantaged have not been ...
Duvarci, Yavuz, Yigitcanlar, Tan
core   +4 more sources

Rental Housing Spot Markets: How Online Information Exchanges Can Supplement Transacted-Rents Data [PDF]

, 2020
Traditional US rental housing data sources such as the American Community Survey and the American Housing Survey report on the transacted market—what existing renters pay each month.
Boeing, Geoff, Jiao, Junfeng, Wegmann, Jake   +2 more
core   +3 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Flex-Route Transit for Smart Cities: A Reinforcement Learning Approach to Balance Ridership and Performance

Smart Cities
A major challenge for modern transit systems relying on traditional fixed-route designs is providing broad accessibility to users. Flex-route transit can enhance accessibility in low-density areas, since it combines the directness of fixed-route transit ...
Joseph Rodriguez, Haris N. Koutsopoulos, Jinhua Zhao   +2 more
doaj   +1 more source

Iterated clustering optimization of the split-delivery vehicle routing problem considering passenger walking distance

Transportation Research Interdisciplinary Perspectives, 2023
The user-oriented, demand-driven nature of customized shuttle bus (CSB) services forces operators to pay more attention to service quality. However, the bus route planning of CSB and other similar systems in established studies rarely took service ...
Jiangbo Wang, Zhirui Lian, Chao Liu, Kai Liu   +3 more
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Feeding Urban Rail Transit: Hybrid Microtransit Network Design Based on Parsimonious Continuum Approach

Information
In recent years, the passenger flow volume of conventional transit in major cities has declined steadily. Ground public transit often suffers from congestion during rush hours caused by frequent stops (e.g., conventional fixed-route buses) or excessively
Qian Ye, Yunyu Zhang, Kunzheng Wang, Xinghua Liu, Chunfu Shao   +4 more
doaj   +1 more source

Performance Measures to Assess Resiliency and Efficiency of Transit Systems [PDF]

, 2017
Transit agencies are interested in assessing the short-, mid-, and long-term performance of infrastructure with the objective of enhancing resiliency and efficiency.
Bartin, Bekir, Deka, Devajyoti, El-Awar, Ayman, Lou, Peng, Morgul, Ender Faruk, Mudigonda, Sandeep, Na, Chaekuk, Nassif, Hani, Zhu, Yuan, Özbay, Kaan   +9 more
core   +1 more source

An investigation into the feasibility and potential benefits of shared taxi services to commuter stations [PDF]

, 2014
Peer reviewedPublisher ...
Nelson, John D., Wright, Steven
core   +2 more sources