Results 81 to 90 of about 63,753 (337)

Data-Driven Modeling of Demand-Responsive Transit: Evaluating Sustainability Across Urban, Rural, and Intercity Scenarios

open access: yesSystems
Demand-responsive transit (DRT) is an innovative public transportation model that dynamically adjusts routes based on passengers’ specific demands. While existing studies offer insights into routing, scheduling, and network design, they remain fragmented,
Yunxi Zhang   +3 more
doaj   +1 more source

Planning Demand-Responsive Transit to reduce inequality of accessibility

open access: hybridTransportation Research Part A: Policy and Practice
D Wang   +2 more
openalex   +2 more sources

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

Optimal Design of Demand-Responsive Feeder Transit Services with Passengers’ Multiple Time Windows and Satisfaction

open access: yesFuture Internet, 2018
This paper presents a mixed-integer linear programming model for demand-responsive feeder transit services to assign vehicles located at different depots to pick up passengers at the demand points and transport them to the rail station.
Bo Sun, Ming Wei, Senlai Zhu
doaj   +1 more source

Transit Performance Measures in California [PDF]

open access: yes, 2016
This research is the result of a California Department of Transportation (Caltrans) request to assess the most commonly available transit performance measures in California. Caltrans wanted to understand performance measures and data used by Metropolitan
Issac, Emily, Rodier, Caroline
core   +1 more source

Chapter 3 - Mobility on demand (MOD) and mobility as a service (MaaS): early understanding of shared mobility impacts and public transit partnerships [PDF]

open access: yes, 2019
Technology is changing the way we move and reshaping cities and society. Shared and on-demand mobility represent notable transportation shifts in the 21st century.
6t   +53 more
core   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Older people and local public transit: Mobility effects of accessibility improvements in Sweden

open access: yesJournal of Transport and Land Use, 2009
Several transportation factors concerning older and disabled people are under transition in Sweden at present. By the year 2010, the public transit system must be fully accessible for all passengers.
Anders Wretstrand   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy