Results 81 to 90 of about 37,908 (263)
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
European Transport Research ReviewAutonomous on-demand services as part of public transport are discussed to improve public transport substantially. A household survey in Karlsruhe, Germany, was conducted among inhabitants of a residential area where a combined autonomous and on-demand ...
Lukas Barthelmes +3 more
doaj +1 more source
Frontiers in Sustainable CitiesWith the rapid pace of urbanization and the subsequent dominance of private vehicle usage, cities are under increasing pressure to offer sustainable alternatives to public transportation.
Utpal Deka, Deepthi Mary Dilip
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Analyzing the aspects of organising paratransit services in Vilnius
Transport, 2013 The main objective of the paper is to analyze some aspects of organising new paratransit services in Vilnius. The main presented scientific problem is the creation of a new transportation system integrating it into the existing one. The system in Vilnius
Darius Bazaras, Alina Verseckienė
doaj +1 more source
Molecular Oncology, EarlyView.Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley +1 more source
Dynamic adaptive policymaking for the sustainable city: The case of automated taxis
International Journal of Transportation Science and Technology, 2017 By 2050, about two-thirds of the world’s people are expected to live in urban areas. But, the economic viability and sustainability of city centers is threatened by problems related to transport, such as pollution, congestion, and parking.
Warren E. Walker, Vincent A.W.J. Marchau
doaj +1 more source
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
A yeast model of 5‐oxoproline accumulation reveals a general toleration to 5‐oxoproline
FEBS Open Bio, EarlyView.Using a yeast model, we show that even high accumulation of 5‐oxoproline causes only mild cellular stress and does not trigger oxidative stress. Instead, cells adapt by activating efflux pumps and diverse protective pathways, suggesting that previously proposed harmful effects of 5‐oxoproline may arise from indirect metabolic imbalances rather than the
Pratiksha Dubey +4 more
wiley +1 more source
FEBS Open Bio, EarlyView.UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
A Logit Approach to Study the Attractiveness of DRT Stops Location: The Case Study of Ragusa, Italy
Future TransportationDemand-Responsive Transport (DRT) services ensure the implementation of more sustainable transport solutions and focuses on the creation of more flexible and personalised public transport systems.
Antonio Russo +4 more
doaj +1 more source