Results 31 to 40 of about 125,000 (238)

Upacicalcet: A Novel Intravenous Calcimimetic Agent for Patients Undergoing Hemodialysis With Secondary Hyperparathyroidism

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Secondary hyperparathyroidism (SHPT) is a common complication in patients receiving maintenance dialysis, driven by calcium and phosphate metabolism disturbances. Calcimimetics are central to the management of SHPT by enhancing calcium‐sensing receptor sensitivity and reducing parathyroid hormone secretion.
Fumihiko Koiwa   +3 more
wiley   +1 more source

Implementation of Advanced Demand Side Management for Microgrid Incorporating Demand Response and Home Energy Management System

open access: yesInfrastructures, 2018
To facilitate the possible technology and demand changes in a renewable-energy dominated future energy system, an integrated approach that involves Renewable Energy Sources (RES)-based generation, cutting-edge communication strategies, and advanced ...
Izaz Zunnurain   +3 more
doaj   +1 more source

Incentive‐based demand response program with self‐reported baseline supported by blockchain technology

open access: yesIET Smart Grid, 2023
This research presents a decentralised incentive‐based demand response (DR) program using blockchain technology. Consumers self‐report baseline to the system operator (SO), the smart contract confirms the validity of the data to execute transactions and ...
Bin Li   +4 more
doaj   +1 more source

Demand side management in China [PDF]

open access: yesIEEE PES General Meeting, 2010
Demand side management has been one of the effective means of load shifting and peak-load shaving. In a system with distributed generations and distributed renewable energy sources, demand response can significantly improve the efficiency of electricity usage and energy saving.
Zhong, J, Liu, K, Kang, C
openaire   +2 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

New real-time demand-side management approach for energy management systems

open access: yesIET Smart Grid, 2019
This study proposes a new demand-side management (DSM) technique, which is characterised by low computational requirements. The proposed technique relies on developing an operational matrix by the device local controller based on the device ...
Wla E. Elamin, Mostafa F. Shaaban
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Home - About - Disclaimer - Privacy