Results 41 to 50 of about 24,379 (255)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Croissance économique des pays émergents et géographie mondiale des pierres précieuses

open access: yesEchoGéo, 2011
Extraction activities evolution is more and more dependent on the increase of demand in the emerging countries. The consequences of this growth on the gemstone mining activities are complex.
Remy Canavesio
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Demand Deposits of Country Banks

open access: yes, 1937
Caption title. ; Mode of access: Internet.
Wall, Norman J., Wall, Norman J.
openaire   +3 more sources

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Distribution, characteristics, metallogenic processes and prospecting potential of terrestrial brine-type lithium deposits in the world and lithium demand situation

open access: yesChina Geology
: In response to the rise of the energy storage industries such as new energy vehicles and the wide application of lithium in various fields worldwide, the global demand for lithium resources has been in explosive growth.
Dian-he Liu   +3 more
doaj   +1 more source

The Results of Statistical Research of the Activities of the World’s Largest Gold Mining Companies

open access: yesУчёт. Анализ. Аудит, 2019
The article presents the main results of statistical research activities of the world’s largest gold mining companies, such as the capitalization of the largest gold producers; revenue growth campaigns in 2016 due to the increase in the price of gold ...
ALEXANDER E. Suglobov, Vorontsov
doaj   +1 more source

Determinants of the savings market in Russia [PDF]

open access: yesBanks and Bank Systems, 2018
The main component of the bank’s efficient operations is a sufficient amount of deposit resources. The sharp devaluation of the national currency, the unstable situation of banks, and a significant number of bankruptcies adversely affected the propensity
Nina Morozko   +2 more
doaj   +1 more source

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