Results 51 to 60 of about 24,379 (255)
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Specifics of the domestic deposit market and its alternatives
The Ukrainian deposit market could be considered efficient if the demand for deposits in all operating banks was equal and interest rates on deposits were optimal. This market would then reflect a model of unrestricted competition. However, in the course
O. Shymanska +2 more
doaj +1 more source
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
The global energy transition has significantly increased copper demand due to its critical role in renewable energy infrastructure. As a leading copper producer, Australia faces the challenge of decarbonising its energy-intensive copper processing ...
Hanrong Huang +2 more
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Penghimpunan Dana dan Profitabilitas Bank Syariah di Indonesia
The study focuses on the impact of savings and demand deposits from wadiah, savings and time deposits from mudharabah on profitability of Indonesian Islamic banks. The research uses nine Islamic banks listed by Indonesia Financial Services Authority (OJK)
Febrya Try Mellianda +1 more
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Decomposição da taxa de variação dos multiplicadores monetários no Brasil
In this study we discuss the pattern of the monetary multipliers in Brazil during the period 1980/1998. For a better understandings of such a pattern the rate of change of the multipliers was decomposed in terms of factors which take into account the ...
Jose W. Rossi
doaj
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
: The demand for graphite resources has been increasing due to its extensive use. Graphite deposits in China are mainly distributed in Heilongjiang, Innner Mogolia, Sichuan, Shanxi and Shandong, characterized by “one old & one new” and “many in east &
Li Sun +4 more
doaj +1 more source

