A deep learning architecture for energy service demand estimation in transport sector for Shared Socioeconomic Pathways. [PDF]
Sci Rep, 2023 Joshi S, Ó Gallachóir B, Glynn J.
europepmc +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Estimating demand with recentered instruments
We develop a new approach to estimating flexible demand models with exogenous supply-side shocks. Our approach avoids conventional assumptions of exogenous product characteristics, putting no restrictions on product entry, despite using instrumental variables that incorporate characteristic variation.
Borusyak, Kirill +2 more
openaire +3 more sources
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
A Bayesian Method for Dynamic Origin-Destination Demand Estimation Synthesizing Multiple Sources of Data. [PDF]
Sensors (Basel), 2021 Yu H, Zhu S, Yang J, Guo Y, Tang T.
europepmc +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
An Estimation of Transport Energy Demand in Turkey via Artificial Neural Networks
Promet (Zagreb), 2019 The transportation sector accounts for nearly 19% of total energy consumption in Turkey, where energy demand increases rapidly depending on the economic and human population growth and the increasing number of motor vehicles.
Muhammed Yasin Çodur, Ahmet Ünal
doaj +1 more source
Model Personalization in Behavioral Interventions using Model-on-Demand Estimation and Discrete Simultaneous Perturbation Stochastic Approximation. [PDF]
Proc Am Control Conf, 2022 Kha RT, Rivera DE, Klasnja P, Hekler E.
europepmc +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
The impact of public health emergencies on hotel demand - Estimation from a new foresight perspective on the COVID-19. [PDF]
Ann Tour Res, 2022 He LY, Li H, Bi JW, Yang JJ, Zhou Q.
europepmc +1 more source