A deep learning architecture for energy service demand estimation in transport sector for Shared Socioeconomic Pathways. [PDF]
Joshi S, Ó Gallachóir B, Glynn J.
europepmc +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
An Estimation of Transport Energy Demand in Turkey via Artificial Neural Networks
The transportation sector accounts for nearly 19% of total energy consumption in Turkey, where energy demand increases rapidly depending on the economic and human population growth and the increasing number of motor vehicles.
Muhammed Yasin Çodur, Ahmet Ünal
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Model Personalization in Behavioral Interventions using Model-on-Demand Estimation and Discrete Simultaneous Perturbation Stochastic Approximation. [PDF]
Kha RT, Rivera DE, Klasnja P, Hekler E.
europepmc +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
A Bayesian Method for Dynamic Origin-Destination Demand Estimation Synthesizing Multiple Sources of Data. [PDF]
Yu H, Zhu S, Yang J, Guo Y, Tang T.
europepmc +1 more source
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
The impact of public health emergencies on hotel demand - Estimation from a new foresight perspective on the COVID-19. [PDF]
He LY, Li H, Bi JW, Yang JJ, Zhou Q.
europepmc +1 more source
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source

