Results 81 to 90 of about 126,602 (263)

Entropy Estimation of Disaggregate Production Functions: An Application to Northern Mexico

open access: yesEntropy, 2014
This paper demonstrates a robust maximum entropy approach to estimating flexible-form farm-level multi-input/multi-output production functions using minimally specified disaggregated data.
Richard E. Howitt, Siwa Msangi
doaj   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Residential Electricity Use Demand Estimation in Khuzestan Province [PDF]

open access: yesجستارهای اقتصادی, 2005
In contrast with other source of energy, electricity besides havinggreat importance in production and consumption, plays an importantrole in economic & social decision – making process.
Elham Pourazarm
doaj  

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Demand unconstraining estimation based on big data warehouse in revenue management systems:framework and challenges

open access: yes大数据, 2017
In order to achieve and exam the unconstrained demand data related to each customer in real time and dynamically from both internal and external data resources,including structured and unstructured information,a big data warehouse framework for demand ...
Peng GUO
doaj  

AN ESTIMATION OF STEEL DEMAND IN IRAN (1967-1999) [PDF]

open access: yesفصلنامه پژوهش‌های اقتصادی ایران, 2001
The objective of the present paper is to explore the role of steel industry in the economy and to investigate its demand determinants. The paper has made attempts to find answers for questions still remaining in steel products market.
Karim Azarbaijani, Mohammadreza Rezaei
doaj  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Reinterpreting demand estimation

open access: yes
This paper clarifies how and why structural demand models (Berry and Haile, 2014, 2024) predict unit-level counterfactual outcomes. We do so by casting structural assumptions equivalently as restrictions on the joint distribution of potential outcomes.
openaire   +2 more sources

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