Results 81 to 90 of about 394,967 (298)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Nonparametric modeling and forecasting electricity demand: an empirical study [PDF]
This paper uses half-hourly electricity demand data in South Australia as an empirical study of nonparametric modeling and forecasting methods for prediction from half-hour ahead to one year ahead.
Han Lin Shang
core
Mathematical Models for Natural Gas Forecasting [PDF]
It is vital for natural gas Local Distribution Companies (LDCs) to forecast their customers\u27 natural gas demand accurately. A significant error on a single very cold day can cost the customers of the LDC millions of dollars.
Brown, Ronald H. +3 more
core +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
In this chapter, we discuss predictive analytics techniques for demand forecasting in inventory control. The techniques surveyed in this chapter originate in the realm of time series analysis and forecasting. We first introduce the notion of time series, then we survey a portfolio of time series models.
openaire +1 more source
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Autoregressive Time Series Forecasting of Computational Demand
We study the predictive power of autoregressive moving average models when forecasting demand in two shared computational networks, PlanetLab and Tycoon.
Sandholm, Thomas
core +1 more source
Forecasting Design Day Demand Using Extremal Quantile Regression [PDF]
Extreme events occur rarely, making them difficult to predict. Extreme cold events strain natural gas systems to their limits. Natural gas distribution companies need to be prepared to satisfy demand on any given day that is at or warmer than an extreme ...
Brown, Ronald H. +4 more
core +1 more source
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source

