Results 91 to 100 of about 626,794 (305)

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

Molecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou, Athina Markou, Eleonora Nicolo, Mara S Serafini, Qiang Zhang, Youbin Zhang, Lorenzo Gerratana, Andrew A. Davis, Huiping Liu, William J Gradishar, Carolina Reduzzi, Massimo Cristofanilli, Evi Lianidou   +12 more
wiley   +1 more source

Smart Home Meter Profiler with Load Authentication, Shock Protection, Fault Proof and Restricted Demand Management

International Journal of Technology, 2019
In this paper, we have designed and installed a shock or fault protection system for a single-phase home electrical system using Circuit Breaker (CB) devices available on the market, bearing in mind that certain product areas do not provide shock ...
shashikumar krishnan, Venkataseshaiah Chinthakunta, Sim Kok Swee   +2 more
doaj   +1 more source

Demand-Side Energy Storage System Management In Smart Grid

, 2012
Demand-Side Energy Storage System Management In Smart ...
Hongjian Sun (1496059), Wei-Yu Chiu (15902411), H Vincent Poor (12090341)   +2 more
core  

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Carbon Lock-Out: Advancing Renewable Energy Policy in Europe

Energies, 2012
As part of its climate strategy, the EU aims at increasing the share of electricity from renewable energy sources (RES-E) in overall electricity generation. Attaining this target poses a considerable challenge as the electricity sector is “locked” into a
Robert Pietzcker, Clemens Heuson, Lion Hirth, Nele Friedrichsen, Melf-Hinrich Ehlers, Felix Creutzig, Paul Lehmann   +6 more
doaj   +1 more source

CCDeW: Climate Change and Demand for Water. [PDF]

, 2003
The Climate Change and Demand for Water Revisited project (CCDeW) revisits and updates the benchmark study by Herrington (1996) and takes advantage of new data sets, regional coverage of demand projections and new methodologies for climate impact ...
Moss, S., Weatherhead, E. K., Knox, Jerry W., Butterfield, R. E., Edmonds, B., Piper, B. S., Downing, T. E.   +6 more
core  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Role of artificial intelligence in smart grid – a mini review

Frontiers in Artificial Intelligence
A smart grid is a structure that regulates, operates, and utilizes energy sources that are incorporated into the smart grid using smart communications techniques and computerized techniques.
M. Balamurugan, Kamala Narayanan, N. Raghu, G. B. Arjun Kumar, V. N. Trupti   +4 more
doaj   +1 more source

The Determination of Load Profiles and Power Consumptions of Home Appliances

Energies, 2018
In recent years, the increment of distributed electricity generation based on renewable energy sources and improvement of communication technologies have caused the development of next-generation power grids known as smart grids.
Fatih Issi, Orhan Kaplan
doaj   +1 more source