Results 91 to 100 of about 4,741 (297)

Older people and local public transit: Mobility effects of accessibility improvements in Sweden

open access: yesJournal of Transport and Land Use, 2009
Several transportation factors concerning older and disabled people are under transition in Sweden at present. By the year 2010, the public transit system must be fully accessible for all passengers.
Anders Wretstrand   +3 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Assessing Public Transit Network Efficiency and Accessibility in Johor Bahru and Penang, Malaysia: A Data-Driven Approach

open access: yesResults in Engineering
This study conducts a comprehensive analysis of public bus transit networks in Johor Bahru and Penang, Malaysia, using General Transit Feed Specification (GTFS) data.
Mahbub Hassan   +5 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Demand-responsive public transportation re-scheduling for adjusting to the joint leisure activity demand

open access: yesInternational Journal of Transportation Science and Technology, 2016
Fixed daily trips such as trips to work/school have fixed departure/arrival times and destination points. The recurrent nature of fixed activities facilitates individuals on making more well-informed decisions about the transport mode selection.
Konstantinos Gkiotsalitis   +1 more
doaj   +1 more source

Computer-Aided Scheduling and Dispatch in Demand-Responsive Transit Services

open access: yes, 2004
Computer-Aided Scheduling and Dispatch in Demand-Responsive Transit Services explores the experiences of selected transit agencies, four contract service providers, and four software vendors, focusing on current practice, successful implementation of ...
Kessler, D. S.
core  

Emissions of demand responsive services as an alternative to conventional transit systems

open access: yes, 2007
The environmental performance of public transport plays a key role in improving air quality in urban areas. An important way of improving existing transit services is to use innovative propulsive systems; however, this needs considerable financial ...
Quadrifoglio, Luca   +4 more
core   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

Development of an Algorithm for Optimal Demand Responsive Relocatable Feeder Transit Networks Serving Multiple Trains and Stations

open access: yesUrban Rail Transit, 2019
Although demand responsive feeder bus operation is possible with human-driven vehicles, it has not been very popular and is mostly available as a special service because of its high operating costs due to intensive labor costs as well as requirement for ...
Young-Jae Lee   +3 more
doaj   +1 more source

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