Results 91 to 100 of about 113,433 (343)

An Assessment of Microtransit Impacts on its Substitution and Complementarity with other Modes

open access: yesFindings
In March of 2022, the Metropolitan Atlanta Rapid Transit Authority, or MARTA, which had previously been a fixed-route system only, implemented a demand-responsive transit system called MARTA Reach.
Maha Ahmad   +4 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Assessing Public Transit Network Efficiency and Accessibility in Johor Bahru and Penang, Malaysia: A Data-Driven Approach

open access: yesResults in Engineering
This study conducts a comprehensive analysis of public bus transit networks in Johor Bahru and Penang, Malaysia, using General Transit Feed Specification (GTFS) data.
Mahbub Hassan   +5 more
doaj   +1 more source

Older people and local public transit: Mobility effects of accessibility improvements in Sweden

open access: yesJournal of Transport and Land Use, 2009
Several transportation factors concerning older and disabled people are under transition in Sweden at present. By the year 2010, the public transit system must be fully accessible for all passengers.
Anders Wretstrand   +3 more
doaj   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Integrated Modeling Approach for the Transportation Disadvantaged [PDF]

open access: yes, 2007
Transportation models have not been adequate in addressing severe long-term urban transportation problems that transportation disadvantaged groups overwhelmingly encounter, and the negative impacts of transportation on the disadvantaged have not been ...
Duvarci, Yavuz, Yigitcanlar, Tan
core   +4 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Home - About - Disclaimer - Privacy