Results 51 to 60 of about 11,791,712 (289)
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
A Domestic Microgrid with Optimized Home Energy Management System
Energies, 2018 Microgrid is a community-based power generation and distribution system that interconnects smart homes with renewable energy sources (RESs). Microgrid efficiently and economically generates power for electricity consumers and operates in both islanded ...
Zafar Iqbal +7 more
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Water demand management for social justice : women, like men, have much to offer in the management of water resources [PDF]
, 2008 French version available in IDRC Digital Library: Gestion de la demande en eau, un instrument de justice sociale : les femmes, comme les hommes, ont beaucoup à offrir en matière de gestion des ressources hydriquesArabic version available in IDRC Digital ...
core +1 more source
Demand-side management for smart grid via diffusion adaptation
IET Smart Grid, 2019 This study presents a novel fully distributed and cooperative demand side management framework based on adaptive diffusion strategy. In this approach, each customer autonomously and without any need for the global information, minimises his incommodity ...
Milad Latifi +4 more
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source
Agent-based control for decentralised demand side management in the smart grid
, 2011 Central to the vision of the smart grid is the deployment of smart meters that will allow autonomous software agents, representing the consumers, to optimise their use of devices and heating in the smart home while interacting with the grid.
Vytelingum, Perukrishnen +3 more
core +1 more source