Results 71 to 80 of about 131,770 (259)

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant   +11 more
wiley   +1 more source

Editorial: Data-Driven Energy Demand Side Management Techniques

open access: yesFrontiers in Energy Research, 2022
Fengji Luo
doaj   +1 more source

Availability and Feasibility of Demand Side Management Projects in Egypt

open access: yesARCHive-SR, 2019
Demand Side Management (DSM) results in energy consumption reduction accompanied by lower cost according to the feasibility study for each project. In Egypt, DSM projects are scarce due to lack of good studies proving their underlining profitability ...
Mohamed Gaber   +3 more
doaj   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

open access: yesFEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani   +6 more
wiley   +1 more source

A Distributed Demand Side Energy Management Algorithm for Smart Grid

open access: yesEnergies, 2019
This paper proposes a model predictive control (MPC) framework-based distributed demand side energy management method (denoted as DMPC) for users and utilities in a smart grid. The users are equipped with renewable energy resources (RESs), energy storage
Min-fan He   +5 more
doaj   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

open access: yesFEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo   +7 more
wiley   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

open access: yesFEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana   +5 more
wiley   +1 more source

Integrated demand response optimization strategy considering risk appetite under multi‐dimensional uncertain information

open access: yesIET Generation, Transmission & Distribution
Integrated demand response (IDR) is deemed as an effective tool to balance energy supply and demand. User’s uncertain information containing prior uncertain information and posterior uncertain information is a key factor affecting the implementation ...
Shunlin Zheng   +7 more
doaj   +1 more source

Demand Side Management in Pellet Production: Internal and External Factors

open access: yesEnvironmental and Climate Technologies, 2014
This paper demonstrates a demand side management case study: how to save energy and how research and data analysis help to create an energy management system in a pellet production facility; and shows ways to implement the EU energy efficiency directive ...
Vigants Haralds   +2 more
doaj   +1 more source

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