Results 11 to 20 of about 59,740 (225)

Dementia With Lewy Bodies: A Review of Disease-Modifying Therapies for α-Synucleinopathies [PDF]

BJPsych Open
Aims: The global demographic transition has led to a growing ageing population. Neurodegenerative disease prevalence is high in the elderly, as aged brains accumulate molecular and cellular damage.
Arzoo Dar, Sharmi Bhattacharyya
doaj   +3 more sources

Sex differences in clinical cognitive impairment with Lewy bodies: a Chinese multicenter study

Biology of Sex Differences, 2022
Highlights There are significant sex differences in Chinese population with cognitive impairment in Lewy body disease. Women were more common in dementia with Lewy bodies and mild cognitive impairment with Lewy bodies cases, had more frequent and severe ...
Jinghuan Gan, Zhichao Chen, Zhihong Shi, Xudong Li, Shuai Liu, Yiming Liu, Hongcan Zhu, Lu Shen, Guili Zhang, Yong You, Qihao Guo, Nan Zhang, Yang Lv, Baozhi Gang, Junliang Yuan, Yong Ji   +15 more
doaj   +1 more source

Improving the diagnosis and management of Lewy body dementia: the DIAMOND-Lewy research programme including pilot cluster RCT

Programme Grants for Applied Research, 2021
Background: Lewy body dementia, comprising both dementia with Lewy bodies and Parkinson’s disease dementia, is the second commonest cause of neurodegenerative dementia.
John T O’Brien, John-Paul Taylor, Alan Thomas, Claire Bamford, Luke Vale, Sarah Hill, Louise Allan, Tracy Finch, Richard McNally, Louise Hayes, Ajenthan Surendranathan, Joseph Kane, Alexandros E Chrysos, Allison Bentley, Sally Barker, James Mason, David Burn, Ian McKeith   +17 more
doaj   +1 more source

Assessment of genetic risk for improved clinical-neuropathological correlations

Acta Neuropathologica Communications, 2020
In the clinical diagnosis of dementia with Lewy bodies, distinction from Alzheimer’s disease is suboptimal and complicated by shared genetic risk factors and frequent co-pathology.
Barbara E. Spencer, Robin G. Jennings, Chun C. Fan, James B. Brewer   +3 more
doaj   +1 more source

Prodromal Dementia With Lewy Bodies and Recurrent Panic Attacks as the First Symptom: A Case Report

Frontiers in Neurology, 2022
Psychiatric-onset dementia with Lewy bodies (DLB) might include symptoms of depression, hallucinations, anxiety, and apathy. Here, we report a patient with DLB with recurrent panic attacks as her first symptom 5 years before a biological-based diagnosis ...
Alberto Jaramillo-Jimenez, Alberto Jaramillo-Jimenez, Alberto Jaramillo-Jimenez, Alberto Jaramillo-Jimenez, Yinbing Ying, Ping Ren, Zhan Xiao, Qian Zhang, Jian Wang, Han Rong, Miguel Germán Borda, Miguel Germán Borda, Miguel Germán Borda, Laura Bonanni, Dag Aarsland, Dag Aarsland, Donghui Wu   +16 more
doaj   +1 more source

Survival and years of life lost in various aetiologies of dementia, mild cognitive impairment (MCI) and subjective cognitive decline (SCD) in Norway. [PDF]

PLoS ONE, 2018
INTRODUCTION:Alzheimer's disease patients are reported to have higher survival rate compared to patients with vascular dementia or dementia with Lewy bodies.
Bjørn Heine Strand, Anne-Brita Knapskog, Karin Persson, Trine Holt Edwin, Rachel Amland, Marit Mjørud, Espen Bjertness, Knut Engedal, Geir Selbæk   +8 more
doaj   +1 more source

Assessing Nigrostriatal Dopaminergic Pathways via 123I-FP-CIT SPECT in Dementia With Lewy Bodies in a Psychiatric Patient Cohort

Frontiers in Aging Neuroscience, 2021
Background(123)-I-2-ß-carbomethoxy-3ß-(4-iodophenyl)-N-(3-fluoropropyl) nortro- pane single photon emission computed tomography (123I-FP-CIT SPECT) was validated to distinguish Alzheimer’s dementia from dementia with Lewy Bodies (DLB) by European medical
Niels Hansen, Claudia Lange, Charles Timäus, Jens Wiltfang, Jens Wiltfang, Jens Wiltfang, Caroline Bouter   +6 more
doaj   +1 more source

Dementia with Lewy bodies - a disease from the border of Neurology and Psychiatry - case report

Journal of Education, Health and Sport, 2017
This article presents the case of 88 years old patient diagnosed and treated for dementia with Lewy bodies.
Lukasz Kroc, Aleksandra Szczepkowska
doaj   +3 more sources

Inflammation in dementia with Lewy bodies

Neurobiology of Disease, 2022
Dementia with Lewy bodies (DLB) is the second most common neurodegenerative cause of dementia, behind Alzheimer's disease (AD). The profile of inflammation in AD has been extensively researched in recent years, with evidence that chronic peripheral ...
Jay Amin, Daniel Erskine, Paul C. Donaghy, Ajenthan Surendranathan, Peter Swann, Amy P. Kunicki, Delphine Boche, Clive Holmes, Ian G. McKeith, John T. O'Brien, Jessica L. Teeling, Alan J. Thomas   +11 more
doaj   +1 more source

Exome sequencing in dementia with Lewy bodies. [PDF]

, 2016
Dementia with Lewy bodies (DLB) is the second most common form of degenerative dementia. Siblings of affected individuals are at greater risk of developing DLB, but little is known about the underlying genetic basis of the disease.
Attems, J, Ayers, KL, Burn, DJ, Chinnery, PF, Cordell, HJ, Douroudis, K, Griffin, H, Hudson, G, Hussein, RI, Keogh, MJ, Kurzawa-Akanbi, M, McKeith, IG, Morris, CM, O'Brien, JT, Pyle, A, Thomas, AJ   +15 more
core   +5 more sources