Results 31 to 40 of about 45,430 (269)
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
THE NORMATIVE PARADOXES OF GLOBALIZATION [PDF]
Following the end of the Cold war, a period of „rule breaking and rule making” has emerged. Its nature is contradictory, exlusionary, based on the power division. The powerfull are rule makers, determining the scope of their relevancy(self-exclusion) and
Radmila NAKARADA
doaj
The Right to Rebel: Social Movements and Civil Disobedience
A fundamental dimension of contemporary social movements is the use of civil disobedience, as means of both exerting mass pressure on the political system and as a process through which the participants of a social movement perceive and construct an ...
Sergio Patricio Fiedler
doaj +1 more source
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Democratic Political Contestation: State, Islam and Media in Indonesia’s Reformative Era
Pada 2 Desember 2018 jutaan Muslim di seluruh negeri berkumpul di Jakarta dan bertemu di jantung ibu kota Indonesia, Monumen Nasional dan sekitarnya (Monas). Ini bukan yang pertama karena setidaknya dua peristiwa serupa yang dikenal sebagai peristiwa 212
Siti Mutiah Setiawati
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Review of empirical studies on political prison in Chile
The objective of this article is to make an exploratory study of the empirical investigations carried out to date on political prison in Chile. These studies are referred entirely to the period of the dictatorship, that is, the period between 1973 and ...
Edison Carrasco Jiménez
doaj +1 more source
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Solidaridad e insolidaridad en el constitucionalismo contemporáneo: elementos para una aproximación
The purpose of this paper is to point out some features of the relationship between solidarity and lack of solidarity in modern and contemporary constitutionalism.
Gerardo Pisarello
doaj +1 more source

