Results 31 to 40 of about 45,430 (269)

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

THE NORMATIVE PARADOXES OF GLOBALIZATION [PDF]

open access: yesBezbednosni Dijalozi, 2010
Following the end of the Cold war, a period of „rule breaking and rule making” has emerged. Its nature is contradictory, exlusionary, based on the power division. The powerfull are rule makers, determining the scope of their relevancy(self-exclusion) and
Radmila NAKARADA
doaj  

The Right to Rebel: Social Movements and Civil Disobedience

open access: yesCosmopolitan Civil Societies: An Interdisciplinary Journal, 2009
A fundamental dimension of contemporary social movements is the use of civil disobedience, as means of both exerting mass pressure on the political system and as a process through which the participants of a social movement perceive and construct an ...
Sergio Patricio Fiedler
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Democratic Political Contestation: State, Islam and Media in Indonesia’s Reformative Era

open access: yesMillati: Journal of Islamic Studies and Humanities, 2020
Pada 2 Desember 2018 jutaan Muslim di seluruh negeri berkumpul di Jakarta dan bertemu di jantung ibu kota Indonesia, Monumen Nasional dan sekitarnya (Monas). Ini bukan yang pertama karena setidaknya dua peristiwa serupa yang dikenal sebagai peristiwa 212
Siti Mutiah Setiawati
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Review of empirical studies on political prison in Chile

open access: yesRevista Facultad de Jurisprudencia, 2018
The objective of this article is to make an exploratory study of the empirical investigations carried out to date on political prison in Chile. These studies are referred entirely to the period of the dictatorship, that is, the period between 1973 and ...
Edison Carrasco Jiménez
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Solidaridad e insolidaridad en el constitucionalismo contemporáneo: elementos para una aproximación

open access: yesRevista de Estudios Sociales, 2013
The purpose of this paper is to point out some features of the relationship between solidarity and lack of solidarity in modern and contemporary constitutionalism.
Gerardo Pisarello
doaj   +1 more source

Home - About - Disclaimer - Privacy