Results 41 to 50 of about 45,430 (269)
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
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Immune System: Is a Trusted Friend, is a Collaborative Enemy?
Forbes Tıp Dergisi, 2022 The immune system is the defense system that creates the reactions of living things, which are at the level of development and ability to distinguish foreign substances in their hereditary structure, against these substances.
Gülden DİNİZ +4 more
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Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
Revista nuestrAmérica, 2019 Resumo: O projeto integralista almejado por Gustavo Barroso baseava-se no modelo de Estado forte. Diferente da postura de Plínio Salgado e Miguel Reale, que não carregavam o racismo contra a figura do judeu, Barroso pensa a formação do novo Brasil com a ...
Cicero João da Costa Filho
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The Role of Law in Resisting Authoritarianism: Lessons from South Africa’s Post-Apartheid Judiciary [PDF]
E-Journal of Humanities, Arts and Social SciencesThis article examines the critical role of law in resisting authoritarianism, with a specific focus on South Africa’s post-apartheid judiciary, particularly the Constitutional Court, as a paradigm of judicial independence within a politically charged ...
Lubabalo Mjadu
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FEBS Open Bio, EarlyView.UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
PENYEDERHANAAN PARTAI POLITIK DALAM SISTEM PEMERINTAHAN PRESIDENSIIL YANG MULTI PARTAI
Yuridika, 2013 Indonesia is a democratic constitutional state that guarantees freedom of association/assembly and freedom of expression under its constitution. The freedom of association is the basic concept of the urge of political parties.
Kuswanto -
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Small RNA pathways in mammalian oocytes
FEBS Open Bio, EarlyView.Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
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FEBS Open Bio, EarlyView.The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
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ПОЛИТИЧКАТА КУЛТУРА НА ЕЛИТИТЕ - ПЕТТИОТ ЕЛЕМЕНТ ВО КОНСОЦИЈАЦИСКИОТ МОДЕЛ НА ДЕМОКРАТИЈА [PDF]
Bezbednosni Dijalozi, 2011 The political consensus of elites is of essential importance for the consolidation of political systems, especially in the deeply divided societies.
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