Results 91 to 100 of about 863,689 (261)

8 The donor of tomorrow: challenges posed by the pandemic, demographic change, and increased transplant requirements. [PDF]

BMJ Open Ophthalmol, 2022
Hofmann N, Schwertner N, Salz AK, Börgel M.   +3 more
europepmc   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Unveiling the Global Economic Impacts from Demographic Change in East Asia: An Estimation and Web Explores

Jurnal Ekonomi Pembangunan
This paper explores the economic consequences of demographic changes on development in 208 countries through 2100. We employ panel fixed effects models to estimate long-run equilibrium relationships between capital stock, labor force, and economic ...
Andin Ardita, Marcus Marktanner
doaj   +1 more source

Modelling the effect of demographic change and healthcare infrastructure on the patient structure in German hospitals - a longitudinal national study based on official hospital statistics. [PDF]

BMC Health Serv Res, 2023
Schoffer O, Schriefer D, Werblow A, Gottschalk A, Peschel P, Liang LA, Karmann A, Klug SJ.   +7 more
europepmc   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Outcome after decompressive craniectomy in older adults after traumatic brain injury

Frontiers in Medicine
ObjectiveGlobally, many societies are experiencing an increase in the number of older adults (>65 years). However, there has been a widening gap between the chronological and biological age of older adults which trend to a more active and social ...
Thomas Kapapa, Stefanie Jesuthasan, Franziska Schiller, Frederike Schiller, Dieter Woischneck, Stefanie Gräve, Eberhard Barth, Benjamin Mayer, Marcel Oehmichen, Andrej Pala   +9 more
doaj   +1 more source

Demographic change and assimilation in the early 21st-century United States. [PDF]

Proc Natl Acad Sci U S A, 2022
Alba R, Maggio C.
europepmc   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Influence of Transit Station Proximity on Demographic Change Including Displacement and Gentrification with Implications for Transit and Land Use Planning After the COVID-19 Pandemic. [PDF]

Transp Res Rec, 2023
Nelson AC, Hibberd R.
europepmc   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source