Results 61 to 70 of about 309,530 (312)

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

How to measure multidimensional quality of life of persons with disabilities in public policies - a case of Poland

open access: yesArchives of Public Health, 2022
Background The aim of this paper is to construct a tool that can be used to measure multidimensional quality of life of persons with disabilities in comparison with population without disabilities for the purpose of monitoring of the UN Convention on the
Izabela Grabowska   +3 more
doaj   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

Demography and the environment [PDF]

open access: yesDemography, 1998
AbstractDemographers' interest in the environment has generally been enmeshed in broader issues of population growth and economic development. Empirical research by demographers on environmental issues other than natural-resource constraints is limited.
openaire   +2 more sources

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

Disciplining anthropological demography [PDF]

open access: yes
This study furthers the epistemological development of anthropological demography, and its role in understanding the demography of Europe. Firstly we situate anthropological demography against the context of an evolving world of research in which ...
Ernestina Coast   +2 more
core  

Sources for an Australian Interdisciplinary Historical Demography

open access: yes, 2019
This chapter begins with quantitative sources: population censuses, vital registration, administrative statistics (including convict records), and sample surveys. This is followed by a short section on the many qualitative sources and a discussion of the
Kippen, Rebecca, Lucas, David
core   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

open access: yesFEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani   +6 more
wiley   +1 more source

Demography in a new key [PDF]

open access: yes
The widespread opinion that demography is lacking in theory is based in part on a particular view of the nature of scientific theory, generally known as logical empiricism [or positivism].
Thomas K. Burch
core  

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