Results 61 to 70 of about 327,986 (310)

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Demography: To the limit [PDF]

open access: yesNature, 2012
More people are surviving to older ages than ever before, pushing life expectancy from birth to unprecedented highs. Further gains will require tackling age-related conditions, across the world, with ramifications for society as a whole.
openaire   +2 more sources

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Disciplining anthropological demography [PDF]

open access: yes
This study furthers the epistemological development of anthropological demography, and its role in understanding the demography of Europe. Firstly we situate anthropological demography against the context of an evolving world of research in which ...
Ernestina Coast   +2 more
core  

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

A long-term photographic dataset for individual identification of the Balearic wall lizard

open access: yesScientific Data
We present BalearicLizard , a curated, long-term collection of high-resolution photographs of the Balearic wall lizard (Podarcis lilfordi) designed to support non-invasive individual re-identification, ecological monitoring and computer-vision ...
Roberto Alcaraz   +5 more
doaj   +1 more source

Demography in a new key [PDF]

open access: yes
The widespread opinion that demography is lacking in theory is based in part on a particular view of the nature of scientific theory, generally known as logical empiricism [or positivism].
Thomas K. Burch
core  

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

open access: yesFEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Cohort Fertility, Parity Progression, and Family Size in Former Yugoslav Countries

open access: yesComparative Population Studies, 2020
Yugoslavia was a union of countries at the crossroads of cultures, rich in diversity, bringing together heterogeneous populations with very different demographic transition pathways, particularly with respect to fertility.
Ivan Čipin   +2 more
doaj   +1 more source

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