Results 41 to 50 of about 69,571 (229)

Multiple Sclerosis Lesion Activity Segmentation with Attention-Guided Two-Path CNNs [PDF]

open access: yesarXiv, 2020
Multiple sclerosis is an inflammatory autoimmune demyelinating disease that is characterized by lesions in the central nervous system. Typically, magnetic resonance imaging (MRI) is used for tracking disease progression. Automatic image processing methods can be used to segment lesions and derive quantitative lesion parameters.
arxiv  

Multiple Sclerosis Lesions Segmentation using Attention-Based CNNs in FLAIR Images [PDF]

open access: yesarXiv, 2022
Objective: Multiple Sclerosis (MS) is an autoimmune, and demyelinating disease that leads to lesions in the central nervous system. This disease can be tracked and diagnosed using Magnetic Resonance Imaging (MRI). Up to now a multitude of multimodality automatic biomedical approaches is used to segment lesions which are not beneficial for patients in ...
arxiv  

Coexistence of Multiple Sclerosis and Brain Tumor: An Uncommon Diagnostic Challenge

open access: yesAdvanced Biomedical Research, 2017
Nonneoplastic demyelinating processes of the brain with mass effect on magnetic resonance imaging can cause diagnostic difficulties. It requires differential diagnosis between the tumefactive demyelinating lesion and the coexistence of neoplasm.
Fatemeh Abrishamchi, Fariborz Khorvash
doaj   +1 more source

Vision-Related Quality of Life in Patients With Atypical Optic Neuritis

open access: yesFrontiers in Pain Research, 2022
AimTo evaluate the vision-related quality of life (QOL) in patients with atypical optic neuritis through the 39-item National Eye Institute Visual Function Questionnaire (NEI VFQ-39).MethodsFifty-seven patients with atypical optic neuritis were scheduled
Zhaocai Jiang   +3 more
doaj   +1 more source

Neuron Signal Propagation Analysis of Cytokine-Storm induced Demyelination [PDF]

open access: yesarXiv, 2021
The COVID-19 pandemic has shaken the world unprecedentedly, where it has affected the vast global population both socially and economically. The pandemic has also opened our eyes to the many threats that novel virus infections can pose for humanity. While numerous unknowns are being investigated in terms of the distributed damage that the virus can do ...
arxiv  

Glial grafting for demyelinating disease [PDF]

open access: yesPhilosophical Transactions of the Royal Society B: Biological Sciences, 2005
Remyelination of demyelinated central nervous system (CNS) axons is considered as a potential treatment for multiple sclerosis, and it has been achieved in experimental models of demyelination by transplantation of pro-myelinating cells. However, the experiments undertaken have not addressed the need for tissue-type matching in order to achieve graft ...
W. F. Blakemore, Vanja Tepavcevic
openaire   +2 more sources

What dominates the time dependence of diffusion transverse to axons: Intra- or extra-axonal water? [PDF]

open access: yes, 2017
Brownian motion of water molecules provides an essential length scale, the diffusion length, commensurate with cell dimensions in biological tissues. Measuring the diffusion coefficient as a function of diffusion time makes in vivo diffusion MRI uniquely sensitive to the cellular features about three orders of magnitude below imaging resolution ...
arxiv   +1 more source

The virology of demyelinating diseases [PDF]

open access: yesAnnals of Neurology, 1994
Infectious agents have been postulated as causes of multiple sclerosis for over a century. The possible role of a virus or viruses is supported by data that (1) a childhood exposure is involved and "viral" infections may precipitate exacerbations of disease, (2) experimental infections in animals and natural infections in humans can cause diseases with
openaire   +3 more sources

Demyelinating neuropathy as the initial presentation of familial E200K Creutzfeldt–Jakob disease in two patients

open access: yesAnnals of Clinical and Translational Neurology
Objective To describe peripheral neuropathy associated with familial Creutzfeldt‐Jakob disease. Methods We report two unrelated patients with genetic Creutzfeldt–Jakob disease with demyelinating peripheral neuropathy as initial presentation, with a ...
Cécile Delorme   +19 more
doaj   +1 more source

Inflammatory demyelinating polyneuropathy versus leptomeningeal disease following Ipilimumab

open access: yesJournal for ImmunoTherapy of Cancer, 2018
Background Ipilimumab is an FDA-approved anti-CTLA-4 monoclonal antibody used in treatment of metastatic melanoma. We present an unusual neurological complication of Ipilimumab therapy and the diagnostic dilemma it caused. Case presentation A 42 year old
Lorraine Cafuir   +4 more
doaj   +1 more source

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