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Journal of Integrative Neuroscience, 2021 Creativity, art and artistic creation in music, dance and visual arts are brain activities specific to humans. Their genetic background remained unexplored for years, but many recent studies have uncovered significant associations with cognition ...
Marinos G. Sotiropoulos +1 more
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Frontiers in Immunology, 2018 Inflammatory demyelinating CNS syndromes include, besides their most common entity multiple sclerosis (MS), several different diseases of either monophasic or recurrent character—including neuromyelitis optica spectrum disorders (NMOSDs) and acute ...
Franziska Di Pauli, Thomas Berger
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Анналы клинической и экспериментальной неврологии, 2018 Optical coherence tomography (OCT) is a non-invasive technique routinely used for obtaining in vivo transverse images of tissues. In the field of neurology, OCT is used to assess retinal changes in various diseases, including multiple sclerosis ...
Natalia V. Polekhina +2 more
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Mechanisms of remyelination: recent insight from experimental models
Biomolecular Concepts, 2014 Oligodendrocytes and myelin play essential roles in the vertebrate central nervous system. Demyelination disrupts saltatory nerve conduction, leading to axonal degeneration and neurological disabilities.
Tanaka Tatsuhide, Yoshida Shigetaka
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Genetics of Demyelinating Diseases
Brain Pathology, 1996 Multiple sclerosis(MS), the prototypic demyelinating disease in humans, is the most common cause of acquired neurological dysfunction arising between early to mid adulthood. MS is an inflammatory disorder and is believed to result from an autoimmune response, directed against myelin proteins and perhaps other antigens, resulting in demyelination and ...
J R, Oksenberg, E, Seboun, S L, Hauser
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Leber hereditary optic neuropathy (LHON) in a 6-year-old boy with a transient spinal cord lesion
The Turkish Journal of PediatricsBackground. Leber hereditary optic neuropathy (LHON) is a maternally inherited mitochondrial disorder that predominantly manifests as bilateral, painless vision loss in young males.
Anıl Gök +5 more
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Optic neuritis in various demyelinating diseases
Неврология, нейропсихиатрия, психосоматикаThe discovery of antibodies against aquaporin-4 (AQP4) and against myelinoligodendrocyte glycoprotein (MOG) confirmed the existence of two disease entities distinct from multiple sclerosis (MS) — neuromyelitis optica spectrum disorders (NMOSD) and ...
A. K. Kalashnikova +8 more
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CSF oligoclonal bands in neurological diseases besides CNS inflammatory demyelinating disorders
BMJ Neurology OpenObjective To understand the distribution characteristics and clinical significance of cerebrospinal fluid (CSF) oligoclonal bands (OCBs) in different nervous system diseases besides typical central nervous system (CNS) inflammatory demyelinating ...
Feng Gao +6 more
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Neuroradiological evaluation of demyelinating disease
Therapeutic Advances in Neurological Disorders, 2013 Central nervous system inflammatory demyelinating disease can affect patients across the life span. Consensus definitions and criteria of all of the different acquired demyelinating diseases that fall on this spectrum have magnetic resonance imaging ...
Jan-Mendelt Tillema, Istvan Pirko
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Advances in Therapeutics Research for Demyelinating Diseases
PharmaceuticalsDemyelinating diseases comprise a group of chronic and debilitating neurological disorders, with the destruction of the myelin sheath serving as the core pathological hallmark. The central pathogenesis involves immune-mediated damage to oligodendrocytes (
Jinhui Jiang +5 more
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