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Nature Reviews Disease Primers, 2020 Neuromyelitis optica (NMO; also known as Devic syndrome) is a clinical syndrome characterized by attacks of acute optic neuritis and transverse myelitis. In most patients, NMO is caused by pathogenetic serum IgG autoantibodies to aquaporin 4 (AQP4), the most abundant water-channel protein in the central nervous system.
Sven, Jarius +5 more
exaly +11 more sources
Indian Journal of Physical Medicine & Rehabilitation, 2009 Neuromyelitis optica (NMO) is a rare, idiopathic,inflammatory disease affecting the spine andcharacteristically sparing the brain. It mimics multiplesclerosis (MS) in many aspects.
Goyal V, Rooru S, Gafoor AS, Sreekala VK
doaj +4 more sources
Annals of Indian Academy of Neurology, 2007 Neuromyelitis optica (NMO) or Devic′s disease was until recently regarded as an unusual or severe variant of multiple sclerosis. However the last decade has seen major advances in our understanding of the etiopathogenesis of NMO. Though unsettled,
Jacob Anu, Boggild Mike
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New onset neuromyelitis optica in a young Nigerian woman with possible antiphospholipid syndrome: a case report [PDF]
Journal of Medical Case Reports, 2008 Introduction Devic's neuromyelitis optica is an inflammatory demyelinating disease that targets the optic nerves and spinal cord. It has a worldwide distribution and distinctive features that distinguish it from multiple sclerosis.
Komolafe Morenikeji A +6 more
doaj +2 more sources
Rheumatic Disease Clinics of North America, 2017 Neuromyelitis optica (NMO), formerly known as Devic disease, is an autoimmune astrocytopathic disease characterized by transverse myelitis and optic neuritis. Most patients demonstrate a relapsing course with incomplete recovery between attacks, resulting in progressive disability.
Sarah L, Patterson, Sarah E, Goglin
+9 more sources
Tidsskrift for Den norske legeforening, 2013 Neuromyelitis optica (NMO) is a rare autoimmune inflammatory disease of the central nervous system that is characterized mainly by recurrent optic neuritis and longitudinally extensive transverse myelitis. The aim of this article is to present current knowledge on the clinical features, diagnosis, pathogenesis and treatment of the condition.The article
Silje Agnethe Stokke, Kvistad +4 more
+5 more sources
The patient journey with NMOSD: From initial diagnosis to chronic condition
Frontiers in Neurology, 2022 ObjectiveTo better understand the patient experience with neuromyelitis optica spectrum disorder (NMOSD) through the course of the illness.BackgroundNMOSD is a rare autoimmune disorder that causes recurrent inflammatory attacks of the optic nerve, spinal
Guillermo Delgado-Garcia +4 more
doaj +1 more source
Neuromyelitis optica spectrum disorders [PDF]
Therapeutic Advances in Neurological DisordersMohammad Ali Sahraian, Kazuo Fujihara
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Scientific Reports, 2021 Neuromyelitis Optica and Multiple Sclerosis are idiopathic inflammatory demyelinating diseases of the central nervous system that currently are considered distinct autoimmune diseases, so differences in genetic susceptibility would be expected.
Marcos Papais Alvarenga +9 more
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Aktuelle Neurologie, 2012 The discovery of serum autoantibodies against the astrocytic water channel aquaporin-4 (AQP4) as a biomarker of neuromyelitis optica (NMO, Devic syndrome) has revolutionized our understanding of this rare immune-mediated clinical entity and has provided a rationale for the use of therapeutic strategies targeting the humoral effector arm of autoimmune ...
B, Wildemann, S, Jarius, F, Paul
+8 more sources